Press release:
01.02.2010
Suicide risk of depressive patients increasing with genetic disposition
Research into genetic causes of suicidal behaviour of depressive patients associates variants of tyrosin kinase 2 receptor gene (NTRK2) with an elevated risk of attempted suicide. As a binding site for the factor BDNF (brain derived neurotrophic factor), NTRK2 has an important function for a target-oriented setting up of networks of nerve cells and thus for a well-balanced neuronal communication. With the newly-discovered mutations, the scientists of the Max Planck Institute of Psychiatry have established the study of the molecular causes of suicidal behaviour....
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