News
| Date: | 16.05.2013 |
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| Abstract: | Differing Traumas in Patients with Posttraumatic Stress Disorder have different Effects on the Biology of the Disease, a Genom-wide Study shows for the first time |
| Date: | 01.05.2013 |
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| Abstract: | The renowned faculty honours Prof. Holsboer's epoch-making contributions to the translational investigation and development of personalized therapy in psychiatry, as well as his constitution of a research institute serving as a model for psychiatric research. |
| Date: | 26.02.2013 |
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| Abstract: | Scientists discover a new - stress hormone independent - mode of action and identify with the protein Homer-1 a key molecule for the development of future anti-stress medication to avoid a decline in cognitive power... |
| Date: | 25.01.2013 |
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| Abstract: | A study in healthy test persons demonstrates for the first time that a high functional connectivity of brain areas of the limbic system can obviously have a regulatory effect on the physical stress response... |
| Date: | 02.12.2012 |
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| Abstract: | Latest studies document that a specific gene-environment interaction can cause the development of psychiatric disorders. Researchers identified defined DNA-sequences in the FKBP5 gene which are the molecular targets of epigenetic changes after stress exposure.... |
| Date: | 27.11.2012 |
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| Abstract: | Rainer Rupprecht and Eric Nestler have been awarded for their breakthroughs in research on the neurobiological basics and pharmacological therapeutics of affective disorders ... |
| Date: | 15.11.2012 |
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| Abstract: | The Swedish neuroscientist Tomas Hökfelt has been decorated for his lifetime achievements on signal transduction between neurons by the "Foundation Deutsche Forschungsanstalt für Psychiatrie". The Golden Kraepelin Medal is one of the most prestigous awards in psychiatric research..... |
| Date: | 18.09.2012 |
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| Abstract: | For the first time, scientists have proved electrophysiologically how the central brain region for learning and memory formation succeeds in extracting important information from a flood of signals and transmitting it so that it can be stored… |
| Date: | 23.07.2012 |
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| Abstract: | Studies of lucid dreamers visualise which centres of the brain become active when we become aware of ourselves... |
| Date: | 30.06.2012 |
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| Abstract: | German prize for medicine honors outstanding findings in research on depression and infectious diseases.... |
| Date: | 30.03.2012 |
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| Abstract: | Max Planck researcher succeed in designing chemical compounds for future antidepressants, to affect the stress factor FKBP51... |
| Date: | 05.03.2012 |
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| Abstract: | For his outstanding achievements in the field of pain research Walter Zieglgänsberger has been decorated by the TU Munich... |
| Date: | 31.01.2012 |
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| Abstract: | Newly discovered Neuropeptid S can reach the brain to unfold anxiolytic effects, by absorption through the nasal mucosa, as has been demonstrated in mice..... |
| Date: | 23.01.2012 |
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| Abstract: | By modern detection methods Max Planck Researcher demonstrate, that most of depressive patients show a change in their molecular stress system.... |
| Date: | 13.01.2012 |
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| Abstract: | Max Planck researchers have proven something scientifically for the first time that laypeople have always known: the mere sight of delicious food stimulates the appetite. The study has documented that the amount of the neurosecretory protein ghrelin in the blood increases as a result of visual stimulation through images of food... |
| Date: | 02.12.2011 |
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| Abstract: | Nobody can be protected from traumatizing experiences, but the development of a PTSD may be prevented by early medicinal intervention. Studies on mice identify CRHR1 antagonists as potential protective drugs of the future.... |
| Date: | 18.11.2011 |
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| Abstract: | Prof. Kerry Ressler from the Emory University of Atlanta got nominated with the Emil Kraepelin Professorship 2011 for his discoveries on the molecular and cellular mechanism of anxiety-related disorders..... |
| Date: | 09.11.2011 |
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| Abstract: | The likelihood of a patient to experience suicidal ideation in the beginning of a therapy with antidepressions can be determined by his individual genetic profile. The knowledge of risk will allow a more intensive care and closer supervision at the onset of therapy.... |
| Date: | 27.10.2011 |
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| Abstract: | With the help of lucid dreamers it has become possible to analyse the activity of the brain during dreaming. Similar brain activity could be measured in dreamed compared to real movements. Studies on lucid dreaming will allow first steps of real "dream reading".... |
| Date: | 08.10.2011 |
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| Abstract: | Within the framework of the opening ceremony of the Polo Científico y Tecnológico in Buenos Aires, Prof. Florian Holsboer has been awarded the Argentine National Award for his personal dedication to promote Science in Argentinia.... |
| Date: | 06.10.2011 |
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| Abstract: | The protein DRR1 is activated by stress and affects the bundling of actin filaments to infuence the architecture of cells. As a result the signal transduction between neurons as well as learning abilities are changed.... |
| Date: | 20.09.2011 |
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| Abstract: | Stress induced neuropeptid Corticotropin-releasing hormone (CRH) can strongly affect learning and memory. Current studies in mice demonstrate that experienced early life stress results in impaired learning as adult. A reduced communication between neurons of specific brain regions, due to fewer synapses, is responsible for this.... |
| Date: | 01.09.2011 |
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| Abstract: | Corticotropin-releasing hormone (CRH) does increase anxiety, but does also reduce it, depending of the area of action within the brain - this is the surprising result of the Max Planck Institute of Psychiatry.... |
| Date: | 10.08.2011 |
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| Abstract: | Patients suffering from anxiety disorders, like PTSD can not forget the frightening events. Scientist of the Max Planck Institute demonstrate now that disrupted REM-sleep may add to this phenomenon... |
| Date: | 26.07.2011 |
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| Abstract: | Federal President Christian Wulf recognises the merits about the special German-Argentine relations for scientific interactions and research cooperations.... |
| Date: | 18.07.2011 |
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| Abstract: | The Federal State of Bavaria supports the development of a new class of active substances for antidepressants with 500.000 Euro. This future drugs should help depressive patients with a dysfunction of their stress hormon regulation in particular... |
| Date: | 12.07.2011 |
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| Abstract: | Functional magnetic resonance tomography allowed scientists of the Max Planck Institute to demonstrate, how the functional connectivity in the brain changes during different sleep stages... |
| Date: | 30.06.2011 |
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| Abstract: | New studies document, that drugs agains depression act on the degradation and recycling process of cells by which the energie-balance and decontamination of the cell is ensured.... |
| Date: | 25.05.2011 |
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| Abstract: | Chronic stress can lead to neurotoxic beta-amyloid protein and hyperphosphorylation of tau-protein, as demonstrated in the rat model. Both processes are main causing factors of the Alzheimer disease in humans... |
| Date: | 27.04.2011 |
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| Abstract: | Genom comparision of healthy and affected subjects identified an aminoacid transporter as disease associated factor in the development of depression... |
| Date: | 07.03.2011 |
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| Abstract: | Beside the admission to this top-class interdisciplinary researcher community a research grant for three years is given... |
| Date: | 21.02.2011 |
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| Abstract: | Current studies document a systematic change in the activity of neuronal networks, responsible for self-reflection and self-perception, while passing from wakefulness to sleep.... |
| Date: | 08.02.2011 |
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| Abstract: | The worldwide biggest private foundation in the field of psychiatric research supports two young group leaders of the institute... |
| Date: | 18.01.2011 |
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| Abstract: | Modern imaging techniques will improve future diagnosis and therapy monitoring of neurological and psychiatric diseases ... |
| Date: | 15.12.2010 |
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| Abstract: | Max Planck researchers identified that the sensitivity to stress is determined by the molecular composition of the AMPA receptor. Potentially this configuration can be determined by behavioral testing to predict the individual risk to develop a stress associated disease... |
| Date: | 13.12.2010 |
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| Abstract: | Max Planck researchers have developed a new GPU enabled tool to analyse genome wide SNIP interactions within days instead of years. This tool is available as download file.... |
| Date: | 05.11.2010 |
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| Abstract: | Measuring brain activity whenever prediction errors occur may help to analyse normal and pathological fear. The prediction error signals is produced when an expected impulse does not appear and the brain tries to adapt and improve the next prediction... |
| Date: | 22.10.2010 |
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| Abstract: | In the course of the 14th Conference of the Neuroendocrinological Section of the German Society of Endocrinology, the close collaboration of the Max Planck Institute of Psychiatry with Argentina, already existing since 1990, was celebrated... |
| Date: | 26.08.2010 |
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| Abstract: | In wakefulness our brain is organized as a “small-world” network. Neighbouring brain regions communicate by many short connections, but have only a few long distance projections to regions far away. Newest studies of the Max Planck Institute of Psychiatry demonstrate that this network organization changes during sleep. This finding allows new insights into the function of sleep for the consolidation of newly acquired information... |
| Date: | 21.07.2010 |
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| Abstract: | The neuropeptid urocortine 3 is involved in the regulation of the hormonal and behavioural reaction to stress. However, a loss of function of urocortin 3 in the brain does not lead to changes in anxiety behaviour. Instead test mice display an improved perception of olfactory stimuli for social recognition and memory of conspecifics. These findings shed new light on the family of CRH alike neuropeptides and on their receptors, the functions of which, as has been shown, go far beyond the mediation of stress-associated behaviour.... |
| Date: | 13.07.2010 |
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| Abstract: | In stress-associated diseases like depression or posttraumatic stress disorder (PTSD), increased concentrations of the neuropeptide Corticotropin-releasing hormone (CRH) are often found in the brain. Therefore, it has been assumed for a long time that increased CRH might be involved in the development of symptoms of a disease such as reduced retentivity or flashbacks. Scientists of the Max Planck Institute of Psychiatry could now visualize that CRH lead to a markedly increased activity propagation in the brain... |
| Date: | 28.06.2010 |
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| Abstract: | Even a single night of partial sleep deprivation can have a negative impact on our cognition and our emotions. Now, scientists identified with the aid of functional magnetic resonance imaging changes in the resting state network activity of the brain as potential cause... |
| Date: | 14.05.2010 |
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| Abstract: | Accidents and catastrophes can neither be predicted nor prevented and victims who are directly involved can therefore not be protected from physical and mental consequences either. This concerns various professions, like firemen, hospital workers or soldiers. This could change in future as it may become possible to determine if helpers are at risk to develop PTSD by recording sleep after induced fear responses... |
| Date: | 26.04.2010 |
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| Abstract: | For patients suffering from phobia or trauma-related anxiety disorder, targeted confrontation with the stimuli or situations triggering fear is the most promising treatment of behaviour therapy. It is, however, emotionally extremely draining that the patients are in most cases for a long time exposed to the stimuli triggering fear. Scientists of the Max Planck Institute of Psychiatry in Munich have recently been able to show in animal experiments that short, but more frequent exposition to the stimuli that trigger fear is significantly more successful with regard to reduction of anxiety... |
| Date: | 07.04.2010 |
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| Abstract: | Pathological anxiety can be caused by many things. It can, however, only develop if the appropriate biological requirements are fulfilled. Now, clinical and preclinical studies document a new genetic cause of pathological anxiety behaviour. In patients concerned, a so-called risk variant of the TMEM132D gene could be identified... |
| Date: | 18.03.2010 |
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| Abstract: | For a long time already, we have known that patients suffering from depression have difficulty in acquiring new knowledge, like e.g. in memorizing word pairs. If their so-called declarative memory is tested, they come off worse than healthy probands. On the other hand, their motor compliance and their sensomotor memory concerning sequences of action is not impaired. Thus, depressive patients learn to type a specific sequence of numbers on a computer keyboard comparably fast... |
| Date: | 01.02.2010 |
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| Abstract: | Research into genetic causes of suicidal behaviour of depressive patients associates variants of tyrosin kinase 2 receptor gene (NTRK2) with an elevated risk of attempted suicide. As a binding site for the factor BDNF (brain derived neurotrophic factor), NTRK2 has an important function for a target-oriented setting up of networks of nerve cells and thus for a well-balanced neuronal communication. With the newly-discovered mutations, the scientists of the Max Planck Institute of Psychiatry have established the study of the molecular causes of suicidal behaviour.... |
| Date: | 26.01.2010 |
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| Abstract: | On January 25th, 2010, the independent jury of the "Cluster of Excellence Competition" of the German Federal Ministry of Culture and Research (BMBF) came to a decision in Berlin. Among the winners is the Munich Application "M4 - A new Dimension in the Development of Drugs". The joint project of the Ludwig Maximilian University of Munich, the Novartis Pharma AG and the MPI of Psychiatry on establishing models for an individualized tumor therapy will be supported with a total of 1,2 million Euros... |
| Date: | 08.11.2009 |
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| Abstract: | Scientists of the Max Planck Institute of Psychiatry have found out how severe mental stress causes attachment of elementary chemical markings - so-called methyl groups - to our genetic material, resulting in permanent alteration of the activity of genes. This was possible by help of mice which were separated from their mothers shortly after birth and, as a consequence of this, showed elevated stress hormones and reduced stress tolerance all their life. In case of corresponding disposition both are precursors to major depression. Decoding of this formation of memory is subject of Epigenetics, a research area becoming more and more important for the comprehension of the interdependency of genes and environment. Thus, scientists hope to develop new therapies which are individuum-tailored... |
| Date: | 30.09.2009 |
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| Abstract: | Approximately 22 million people in Europe are dyslexic. Not to be able to read and write in spite of attending school and being supported by their parents to a great extent puts strain on many adolescents and not rarely leads to drop out of school and mental problems. A German Research Consortium have for the first time ever found a genetic cause of malfunctioning language processing of dyslexic children... |
| Date: | 07.09.2009 |
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| Abstract: | It still remains unanswered up to now why treatment with antidepressants is not sufficiently successful in 30 % of the patients suffering from depression. Scientists of the Max Planck Institute of Psychiatry in Munich studied this phenomenon via analysis of genetic and clinical parameters of the patients in order to find out which factors predict therapeutic success.... |
| Date: | 03.09.2009 |
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| Abstract: | Sleep is a vital process and loss of sleep leads to massive damage of our cognitive efficiency. Therefore, it is of decisive importance for our brain to be able to fall asleep and to maintain sleep in spite of continuous environmental stimuli (e.g. street noise). On the other hand, we can be awoken at any time by stimuli that are strong enough. How does our brain then process external stimuli during sleep? ... |
| Date: | 26.08.2009 |
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| Abstract: | In the meantime, it is 20 years old: the Zülch-Prize. Every year, it is awarded for extraordinary achievements in neurological basic research. This year, two scientists exploring the causes of psychiatric diseases on molecular basis will be honoured: Florian Holsboer, Director of the Max Planck Institute of Psychiatry in Munich, and Daniel R. Weinberger from the National Institute of Mental Health in Bethesda, Maryland/USA will accept the award on September 11th in Cologne... |
| Date: | 18.06.2009 |
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| Abstract: | Every seventh German develops an anxiety disorder that requires treatment. The current anxiolytic drugs are based on the agent class Benzodiazepines and lead to rapid tranquilization and reduction of anxiety. Undesired side effects like sedation, developing of drug resistance and addiction after prolonged intake, however, turn them into problematic drugs... |
| Date: | 01.06.2009 |
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| Abstract: | Depression and anxiety disorders are often caused by stress. Mostly, patients have typical sleep disturbances. Primarily, their dreamphases are more intensive and occur more often. Scientists of the Max Planck Institute of Psychiatry could now clarified, which symptoms being typical of depression and anxiety are associated with the regulation of stress hormones within the brain by using a mouse model... |
| Date: | 20.05.2009 |
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| Abstract: | Without a perceptible trigger mechanism, patients suffering from panic disorder repeatedly experience situations of massive anxiety, which are often accompanied by physical perceptions like tachycardia, shortness of breath and nausea. Indeed, these sensations are caused by malfunction of the brain... |
| Date: | 20.01.2009 |
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| Abstract: | During the past years, basic research at the MPI of Psychiatry has identified the FK506 binding protein 51 (FKBP-51) as a possible target structure for treatment of depression.... |
| Date: | 02.12.2008 |
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| Abstract: | For her outstanding empirical work in the field of basic psychiatric research, Dr. Binder has been awarded the above-mentioned research prize worth 10 000 Euro. Prof. Hans-Jürgen Möller, chairman of the board of trustees, presented the prize at this year`s Congress of the German Society of Psychiatry, Psychotherapy and Neurology (DGPPN) at the end of November in Berlin... |
| Date: | 30.10.2008 |
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| Abstract: | For her outstanding achievements in the field of Clinical Neurosciences, the Max Planck Institute of Psychiatry honoured Professor Helen Mayberg by appointing her Emil Kraepelin Professor 2008. A joint symposium of the MPI and the Emory University School of Medicine, Atlanta/USA on October 29th about „New Therapeutic Findings in Depression“ provided the special setting for this award... |
| Date: | 09.10.2008 |
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| Abstract: | Prof. Florian Holsboer has been awarded the renowned Aschoff-Medal by the Medical Society of Freiburg for his medical and scientific achievements. On October 8th, the anniversary of the death of Ludwig Aschoff, the Society has honoured this year`s prize winner in the course of the Aschoff-Lecture... |
| Date: | 18.09.2008 |
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| Abstract: | Based on his outstanding research accomplishments the Max Planck Society appointed Dr. Damian Refojo as Independent Junior Research Group Leader. Dr. Refojo’s appointment will be start within this year at the Max Planck Institute of Psychiatry and is part of a special support programme to strengthen the scientific collaboration between Germany and Argentina... |
| Date: | 01.09.2008 |
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| Abstract: | The external scientific member of the Max Planck Institute of Psychiatry, Professor Eduard Arzt, Director of the Laboratorio de Fisiología y Biología Molecular of the University of Buenos Aires, is winner of the Bunge y Born Prize 2008. |
| Date: | 28.07.2008 |
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| Abstract: | Patients with Restless Legs Syndrome (RLS) suffer from paresthesia in the legs predominantly occurring during the night. They report on an intensive urge to move which makes a quiet sleep impossible. By carrying out genetic investigations, physicians and scientists have been trying to find out what causes the disease for years already. Now, PTPRD has been successfully identified as a new risk gene for RLS ... |
| Date: | 29.05.2008 |
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| Abstract: | Affective disorders like depression are often accompanied by an increased release of the stress hormone CRH (corticotropin-releasing hormone) within the brain. As proved by clinical studies, only normalization of the CRH activity leads to a successful therapy. Scientists at the Max-Planck-Institute of Psychiatry in Munich have succeeded in provoking an increased CRH activity in specific brain regions of mice, so that the pathophysiological processes of stress-induced diseases can be studied on molecular, cellular and neuronal level... |
| Date: | 07.03.2008 |
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| Abstract: | For the third time within the last 10 years, Irving Kirsch, psychologist and expert on hypnosis, has presented an analysis according to which antidepressants are only efficient in case of rather severe depression. The conclusions drawn by Kirsch don’t have any clinical validity ... |
| Date: | 23.01.2008 |
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| Abstract: | A patient’s profile of his/her ABCB-1 gene enables to predict whether he/she will respond well to a certain drug or not. This finding is another important step towards a personalized therapy for depression ... |
| Date: | 21.01.2008 |
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| Abstract: | In a ceremonial act the honoury doctorate will be bestowed upon Professor Florian Holsboer at the University of Leiden on February 8th, 2008. With this award the oldest University of the Netherlands will honour the outstanding performances .... |
| Date: | 14.01.2008 |
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| Abstract: | Scientists at the Max Planck Institute of Psychiatry in Munich demonstrate, that adolescents and young adults show increasing suicidal tendency if they have a higher consumption of tobacco. The risk to make a suicide attempt increases... |
| Date: | 19.10.2007 |
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| Abstract: | Researchers have identified a molecular switch that governs the reactivity to and specificity of stress. Stress requires specific reactions in order to carry out immediate and effective measures... |
| Date: | 19.07.2007 |
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| Abstract: | Munich-based researchers at the Max Planck Institute of Psychiatry and the Institutes of Human Genetics of both Technical University and GSF (National Research Center for Environment and Health) have succeeded in detecting genetic variants that can elicit nocturnal restlessness in legs up to insomnia... |
| Date: | 18.07.2007 |
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| Abstract: | According to a current study carried out at the Max Planck Institute of Psychiatry depressive patients that are overweight are explicitly less responsive to treatment with antidepressants... |
| Date: | 21.06.2007 |
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| Abstract: | The Max Planck Society appoints Professor Rainer Rupprecht, professor of psychiatry at the Psychiatric Hospital of Ludwig Maximilian University, Munich, as Max Planck Fellow. Thus the Society acknowledges a young and dedicated clinician and promotes his basic and applied clinical research... |
| Date: | 01.04.2007 |
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| Abstract: | Scientists at the Max Planck Institute of Psychiatry succeed in high-resolution 3D-reconstruction of neuronal structures of the mouse brain... |
| Date: | 01.03.2007 |
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| Abstract: | While sleeping our senses are, to a large extent, cut off from the outside world, unless an alarm clock ends our dreams rather abruptly. Occasionally, however, the sound of an alarm clock does not wake us up; it is incorporated into dreaming – and we oversleep. For the first time scientists of the Max Planck Institute of Psychiatry, Munich, could demonstrate how the brain acts in different dream phases... |


