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Susanne Lucae

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Susanne Lucae, Dr. med. univ. Dr. rer. nat.

Research group leader
Text Link Intern RG Lucae: Psychiatric Pharmacogenetics
Phone: 089/30622-608
Fax: 089/30622-605
Email: lucae[a]mpipsykl.mpg.de
Interests: Pharmacogenetics, major depression, HPA-axis, genome-wide association studies, candidate genes, metabolic changes in depression
   
CV:
Born in Dornbirn, Austria. Study of biology and medicine at the University of Vienna, Austria. Postdoc at the Institute of Pathophysiology, University Vienna. Since 2003 at the Max Planck Institute of Psychiatry and Head of the research group Psychiatric Pharmacogenetics since 2007.
Selected publications:
Kohli MA, Lucae S, Saemann PG, Schmidt MV, Demirkan A, Hek K, Czamara D, Alexander M, Salyakina D, Ripke S, Hoehn D, Specht M, Menke A, Hennings J, Heck A, Wolf C, Ising M, Schreiber S, Czisch M, Müller MB, Uhr M, Bettecken T, Becker A, Schramm J, Rietschel M, Maier W, Bradley B, Ressler KJ, Nöthen MM, Cichon S, Craig IW, Breen G, Lewis CM, Hofman A, Tiemeier H, van Duijn CM, Holsboer F, Müller-Myhsok B, Binder EB. The neuronal transporter gene SLC6A15 confers risk to major depression. Neuron. 2011 Apr 28;70(2):252-65.

Lucae S, Ising M, Horstmann S, Baune BT, Arolt V, Müller-Myhsok B, Holsboer F, Domschke K. HTR2A gene variation is involved in antidepressant treatment response. Eur Neuropsychopharmacol. 2010 Jan;20(1):65-8.

Kloiber S, Kohli MA, Brueckl T, Ripke S, Ising M, Uhr M, Menke A, Unschuld PG, Horstmann S, Salyakina D, Muller-Myhsok B, Binder EB, Holsboer F, Lucae S. Variations in tryptophan hydroxylase 2 linked to decreased serotonergic activity are associated with elevated risk for metabolic syndrome in depression. Mol Psychiatry. 2010 Jul;15(7):736-47. Erratum in: Mol Psychiatry 2010 Nov;15(11):1123.

Kloiber S, Ising M, Reppermund S, Horstmann S, Dose T, Majer M, Zihl J, Pfister H, Unschuld PG, Holsboer F, Lucae S (2007) Overweight and Obesity Affect Treatment Response in Major Depression. Biol Psychiatry; 62 (4): 321-6

Erhardt A, Lucae S, Unschuld PG, Ising M, Kern N, Salyakina D, Lieb R, Uhr M, Binder EB, Keck ME, Muller-Myhsok B, Holsboer F (2007) Association of polymorphisms in P2RX7 and CaMKKb with anxiety disorders. J Affective Disorders; 101(1-3): 159-68

Lucae S, Salyakina D, Barden N, Harvey M, Gagne B, Labbe M, Binder EB, Uhr M, Paez-Pereda M, Sillaber I, Ising M, Bruckl T, Lieb R, Holsboer F, Muller-Myhsok B (2006) P2RX7, a gene coding for a purinergic ligand-gated ion channel, is associated with major depressive disorder. Hum Mol Genet 15(16):2438-45

Binder EB, Salyakina D, Lichtner P, Wochnik GM, Ising M, Putz B, Papiol S, Seaman S, Lucae S, Kohli MA, Nickel T, Kunzel HE, Fuchs B, Majer M, Pfennig A, Kern N, Brunner J, Modell S, Baghai T, Deiml T, Zill P, Bondy B, Rupprecht R, Messer T, Kohnlein O, Dabitz H, Bruckl T, Muller N, Pfister H, Lieb R, Mueller JC, Lohmussaar E, Strom TM, Bettecken T, Meitinger T, Uhr M, Rein T, Holsboer F, Muller-Myhsok B (2004) Polymorphisms in FKBP5 are associated with increased recurrence of depressive episodes and rapid response to antidepressant treatment. Nature Genetics 36(12):1319-1325