Chadi Touma
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Chadi Touma, Dr. rer. nat.Research group leader |
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| Phone: | 089/30622-228 | |
| Fax: | 089/30622-569 | |
| Email: | touma[a]mpipsykl.mpg.de | |
| Interests: | Function and Regulation of the Stress Hormone Systems, Stress-related Disorders, Molecular Bases of Behaviour, Gene-Environment Interactions | |
| CV: Born in Bonn, Germany. Studies of Biochemistry and Biology at the Universities of Hanover and Münster, Germany. PhD in Biology (2003) at the Westfälische Wilhelms-University (WWU) Münster (supported by a grant from the ‘Studienstiftung des deutschen Volkes’). Postdoc at the Institute of Biochemistry, University of Veterinary Medicine Vienna, Austria (2003-2004) and the Max Planck Institute of Psychiatry, Munich, Germany (2004-2009). Since 2010, Head of the Research Group ‘Psychoneuroendocrinology’ at the MPI of Psychiatry. |
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Further activities:
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| Selected publications: Knapman A, Kaltwasser SF, Martins-de-Souza D, Holsboer F, Landgraf R, Turck CW, Czisch M, Touma C (2012) Increased stress reactivity is associated with reduced hippocampal activity and neuronal integrity along with changes in energy metabolism. European Journal of Neuroscience 35: 412-422. Touma C, Gassen NC, Herrmann L, Cheung-Flynn J, Büll DR, Ionescu IA, Heinzmann JM, Knapman A, Siebertz A, Depping AM, Hartmann J, Hausch F, Schmidt MV, Holsboer F, Ising M, Cox MB, Schmidt U, Rein T (2011) FK506 binding protein 5 (FKBP5) shapes stress responsiveness: modulation of neuroendocrine reactivity and coping behavior. Biological Psychiatry 70: 928-936. Knapman A, Heinzmann JM, Hellweg R, Holsboer F, Landgraf R, Touma C (2010): Increased stress reactivity is associated with cognitive deficits and decreased hippocampal brain-derived neurotrophic factor in a mouse model of affective disorders. Journal of Psychiatric Research 44: 566-575. Touma C, Fenzl T, Ruschel J, Palme R, Holsboer F, Kimura M, Landgraf R (2009): Rhythmicity in mice selected for extremes in stress reactivity: behavioural, endocrine and sleep changes resembling endophenotypes of major depression. PLoS ONE 4 (1): e4325. Touma C, Bunck M, Glasl L, Nussbaumer M, Palme R, Stein H, Wolferstätter M, Zeh R, Zimbelmann M, Holsboer F, Landgraf R (2008): Mice selected for high versus low stress reactivity: a new animal model for affective disorders. Psychoneuroendocrinology 33: 839-862. Touma C, Palme R, Sachser N (2004): Analyzing corticosterone metabolites in fecal samples of mice: a noninvasive technique to monitor stress hormones. Hormones and Behavior 45: 10-22. |
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