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Carsten Wotjak


Carsten Wotjak, PD Dr. rer. nat.

Research group leader
Text Link Intern RG Wotjak: Neuronal Plasticity
Phone: 089/30622-652
Fax: 089/30622-610
Email: wotjak[a]
Interests: Fear, anxiety, stress, psychopharmacology, neuronal plasticity, endocannabinoid system of the brain, learning and memory, memory extinction/erasure
Born 1970 in Leipzig. Study of biology at the University of Leipzig (1988-1993). From 1993 to 1996 Ph.D. student of Rainer Landgraf at the Max-Planck-Institute of Psychiatry / Universtiy of Munich. 1997 Otto-Hahn Medal of the Max-Planck-Society for outstanding PhD thesis. From 1997 to 1999 postdoctoral fellow at the Center for Molecular Neurobiology Hamburg (ZMNH) in the group of Melitta Schachner. 1999 postdoctoral fellow at the National Institute for Medical Research (Mill Hill / London) in the group of Tim Bliss. Since 2000 leader of the research group Neuronal Plasticity at the Max-Planck-Institute of Psychiatry (Munich). 2011 Habilitation in Neurobiology (Ludwig-Maximilians University Munich).
Selected publications:
Plendl W, Wotjak CT (2010). Dissociation of within-session and between-session extinction of conditioned fear. J Neurosci 30: 4990-4998. [selected for Faculty 1000]

Siegmund A, Kaltwasser SF, Holsboer F, Czisch M, Wotjak CT (2009). Hippocampal NAA levels before trauma predict the development of long-lasting PTSD-like symptoms in mice. Biol Psychiat 65: 258-262.

Murgatroyd C, Patchev AV, Wu Y, Micale V, Bockmühl Y, Fischer D, Holsboer F, Wotjak CT, Almeida OFX, Spengler D (2009). Dynamic DNA methylation programs persistent adverse effects of early-life stress. Nature Neurosci 12: 1559-1566. [selected for Faculty 1000]

Marsch R, Foeller E, Rammes G, Bunck M, Kössl M, Holsboer F, Zieglgänsberger W, Landgraf R, Lutz B, Wotjak CT (2007). Reduced anxiety, conditioned fear and hippocampal LTP in TRPV1 receptor-deficient mice. J Neurosci 27: 832-839.

Kamprath K, Marsicano G, Tang J, Monory K, Bisogno T, Di M, V, Lutz B, Wotjak CT (2006) Cannabinoid CB1 receptor mediates fear extinction via habituation-like processes. J Neurosci 26: 6677-6686

Marsicano G*, Wotjak CT*, Azad SC, Bisogno T, Rammes G, Cascio MG, Hermann H, Tang J, Hofmann C, Zieglgansberger W, Di Marzo V, Lutz B (2002) The endogenous cannabinoid system controls extinction of aversive memories. Nature 418: 530-534. (*shared first authorship)