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Publications of RG Müller-Myhsok since 2002

Czibere, L., L. A. Baur, A. Wittmann, K. Gemmeke, A. Steiner, P. Weber, B. Putz, N. Ahmad, M. Bunck, C. Graf, R. Widner, C. Kuhne, M. Panhuysen, B. Hambsch, G. Rieder, T. Reinheckel, C. Peters, F. Holsboer, R. Landgraf, and J. M. Deussing (2011) Profiling trait anxiety: transcriptome analysis reveals cathepsin B (ctsb) as a novel candidate gene for emotionality in mice. PLoS.One. 6:e23604.

 

Wilcke, A., C. Ligges, J. Burkhardt, M. Alexander, C. Wolf, E. Quente, P. Ahnert, P. Hoffmann, A. Becker, B. Muller-Myhsok, S. Cichon, J. Boltze, and H. Kirsten. 2011. Imaging genetics of FOXP2 in dyslexia. Eur.J.Hum.Genet.10.

 

Winkelmann, J., D. Czamara, B. Schormair, F. Knauf, E. C. Schulte, C. Trenkwalder, Y. Dauvilliers, O. Polo, B. Hogl, K. Berger, A. Fuhs, N. Gross, K. Stiasny-Kolster, W. Oertel, C. G. Bachmann, W. Paulus, L. Xiong, J. Montplaisir, G. A. Rouleau, I. Fietze, J. Vavrova, D. Kemlink, K. Sonka, S. Nevsimalova, S. C. Lin, Z. Wszolek, C. Vilarino-Guell, M. J. Farrer, V. Gschliesser, B. Frauscher, T. Falkenstetter, W. Poewe, R. P. Allen, C. J. Earley, W. G. Ondo, W. D. Le, D. Spieler, M. Kaffe, A. Zimprich, J. Kettunen, M. Perola, K. Silander, I. Cournu-Rebeix, M. Francavilla, C. Fontenille, B. Fontaine, P. Vodicka, H. Prokisch, P. Lichtner, P. Peppard, J. Faraco, E. Mignot, C. Gieger, T. Illig, H. E. Wichmann, B. Muller-Myhsok, and T. Meitinger (2011) Correction: genome-wide association study identifies novel restless legs syndrome susceptibility Loci on 2p14 and 16q12.1. PLoS.Genet. 7:10-4770.

 

Klengel, T., A. Heck, H. Pfister, T. Bruckl, J. M. Hennings, A. Menke, D. Czamara, B. Muller-Myhsok, and M. Ising (2011) Somatization in major depression - clinical features and genetic associations. Acta Psychiatr.Scand. 124:317-328.

 

Glas, J., J. Seiderer, D. Fischer, B. Tengler, S. Pfennig, M. Wetzke, F. Beigel, T. Olszak, M. Weidinger, B. Goke, T. Ochsenkuhn, M. Folwaczny, B. Muller-Myhsok, J. Diegelmann, D. Czamara, and S. Brand (2011) Pregnane X receptor (PXR/NR1I2) gene haplotypes modulate susceptibility to inflammatory bowel disease. Inflamm.Bowel.Dis. 17:1917-1924.

 

Winkelmann, J., D. Czamara, B. Schormair, F. Knauf, E. C. Schulte, C. Trenkwalder, Y. Dauvilliers, O. Polo, B. Hogl, K. Berger, A. Fuhs, N. Gross, K. Stiasny-Kolster, W. Oertel, C. G. Bachmann, W. Paulus, L. Xiong, J. Montplaisir, G. A. Rouleau, I. Fietze, J. Vavrova, D. Kemlink, K. Sonka, S. Nevsimalova, S. C. Lin, Z. Wszolek, C. Vilarino-Guell, M. J. Farrer, V. Gschliesser, B. Frauscher, T. Falkenstetter, W. Poewe, R. P. Allen, C. J. Earley, W. G. Ondo, W. D. Le, D. Spieler, M. Kaffe, A. Zimprich, J. Kettunen, M. Perola, K. Silander, I. Cournu-Rebeix, M. Francavilla, C. Fontenille, B. Fontaine, P. Vodicka, H. Prokisch, P. Lichtner, P. Peppard, J. Faraco, E. Mignot, C. Gieger, T. Illig, H. E. Wichmann, B. Muller-Myhsok, and T. Meitinger (2011) Genome-wide association study identifies novel restless legs syndrome susceptibility loci on 2p14 and 16q12.1. PLoS.Genet. 7:e1002171.

 

Schosser, A., A. W. Butler, M. Ising, N. Perroud, R. Uher, M. Y. Ng, S. Cohen-Woods, N. Craddock, M. J. Owen, A. Korszun, L. Jones, I. Jones, M. Gill, J. P. Rice, W. Maier, O. Mors, M. Rietschel, S. Lucae, E. B. Binder, M. Preisig, J. Perry, F. Tozzi, P. Muglia, K. J. Aitchison, G. Breen, I. W. Craig, A. E. Farmer, B. Muller-Myhsok, P. McGuffin, and C. M. Lewis (2011) Genomewide association scan of suicidal thoughts and behaviour in major depression. PLoS.One. 6:e20690.

 

Altmann, A., P. Weber, C. Quast, M. Rex-Haffner, E. B. Binder, and B. Muller-Myhsok (2011) vipR: variant identification in pooled DNA using R. Bioinformatics. 27:i77-i84.

 

Kam-Thong, T., B. Putz, N. Karbalai, B. Muller-Myhsok, and K. Borgwardt (2011) Epistasis detection on quantitative phenotypes by exhaustive enumeration using GPUs. Bioinformatics. 27:i214-i221.

 

Schormair, B., J. Plag, M. Kaffe, N. Gross, D. Czamara, W. Samtleben, P. Lichtner, A. Strohle, I. Stefanidis, A. Vainas, E. Dardiotis, G. K. Sakkas, C. Gieger, B. Muller-Myhsok, T. Meitinger, U. Heemann, G. M. Hadjigeorgiou, K. Oexle, and J. Winkelmann (2011) MEIS1 and BTBD9: genetic association with restless leg syndrome in end stage renal disease. J.Med.Genet. 48:462-466.

 

Glas, J., J. Seiderer, C. Tillack, E. Paschos, M. Wetzke, J. Diegelmann, D. Czamara, and S. Brand (2011) Functional SFTPD gene variants are not associated with susceptibility to inflammatory bowel disease in the German population. Inflamm.Bowel.Dis. 17:1439-1440.

 

Glas, J., J. Seiderer, C. Fries, C. Tillack, S. Pfennig, M. Weidinger, F. Beigel, T. Olszak, U. Lass, B. Goke, T. Ochsenkuhn, C. Wolf, P. Lohse, B. Muller-Myhsok, J. Diegelmann, D. Czamara, and S. Brand (2011) CEACAM6 gene variants in inflammatory bowel disease. PLoS.One. 6:e19319.

 

Mehta, D., M. Gonik, T. Klengel, M. Rex-Haffner, A. Menke, J. Rubel, K. B. Mercer, B. Putz, B. Bradley, F. Holsboer, K. J. Ressler, B. Muller-Myhsok, and E. B. Binder (2011) Using Polymorphisms in FKBP5 to Define Biologically Distinct Subtypes of Posttraumatic Stress Disorder: Evidence From Endocrine and Gene Expression Studies. Arch.Gen.Psychiatry. 68:901-910.

 

Kohli, M. A., S. Lucae, P. G. Saemann, M. V. Schmidt, A. Demirkan, K. Hek, D. Czamara, M. Alexander, D. Salyakina, S. Ripke, D. Hoehn, M. Specht, A. Menke, J. Hennings, A. Heck, C. Wolf, M. Ising, S. Schreiber, M. Czisch, M. B. Muller, M. Uhr, T. Bettecken, A. Becker, J. Schramm, M. Rietschel, W. Maier, B. Bradley, K. J. Ressler, M. M. Nothen, S. Cichon, I. W. Craig, G. Breen, C. M. Lewis, A. Hofman, H. Tiemeier, C. M. van Duijn, F. Holsboer, B. Muller-Myhsok, and E. B. Binder (2011) The neuronal transporter gene SLC6A15 confers risk to major depression. Neuron. 70:252-265.

 

Sarapas, C., G. Cai, L. M. Bierer, J. A. Golier, S. Galea, M. Ising, T. Rein, J. Schmeidler, B. Muller-Myhsok, M. Uhr, F. Holsboer, J. D. Buxbaum, and R. Yehuda (2011) Genetic markers for PTSD risk and resilience among survivors of the World Trade Center attacks. Dis.Markers. 30:101-110.

 

Weber, F., S. Cepok, C. Wolf, A. Berthele, M. Uhr, T. Bettecken, D. Buck, H. P. Hartung, F. Holsboer, B. Muller-Myhsok, and B. Hemmer (2011) Single-nucleotide polymorphisms in HLA- and non-HLA genes associated with the development of antibodies to interferon-beta therapy in multiple sclerosis patients. Pharmacogenomics.J. 19.

 

Moskvina, V., N. Craddock, B. Muller-Myhsok, T. Kam-Thong, E. Green, P. Holmans, M. J. Owen, and M. C. O'Donovan (2011) An examination of single nucleotide polymorphism selection prioritization strategies for tests of gene-gene interaction. Biol.Psychiatry. 70:198-203.

 

Nischwitz, S., B. Muller-Myhsok, and F. Weber (2011) Risk conferring genes in multiple sclerosis. FEBS Lett. 2011 Mar 23. [Epub ahead of print]

 

Heck, A., H. Pfister, D. Czamara, B. Muller-Myhsok, B. Putz, S. Lucae, J. Hennings, and M. Ising (2011) Evidence for associations between MDGA2 polymorphisms and harm avoidance - replication and extension of a genome-wide association finding. Psychiatr.Genet. 21:257-260.

 

Couturier, N., F. Bucciarelli, R. N. Nurtdinov, M. Debouverie, C. Lebrun-Frenay, G. Defer, T. Moreau, C. Confavreux, S. Vukusic, I. Cournu-Rebeix, R. H. Goertsches, U. K. Zettl, M. Comabella, X. Montalban, P. Rieckmann, F. Weber, B. Muller-Myhsok, G. Edan, B. Fontaine, L. T. Mars, A. Saoudi, J. R. Oksenberg, M. Clanet, R. S. Liblau, and D. Brassat (2011) Tyrosine kinase 2 variant influences T lymphocyte polarization and multiple sclerosis susceptibility. Brain. 134:693-703.

 

Cichon, S., T. W. Muhleisen, F. A. Degenhardt, M. Mattheisen, X. Miro, J. Strohmaier, M. Steffens, C. Meesters, S. Herms, M. Weingarten, L. Priebe, B. Haenisch, M. Alexander, J. Vollmer, R. Breuer, C. Schmal, P. Tessmann, S. Moebus, H. E. Wichmann, S. Schreiber, B. Muller-Myhsok, S. Lucae, S. Jamain, M. Leboyer, F. Bellivier, B. Etain, C. Henry, J. P. Kahn, S. Heath, M. Hamshere, M. C. O'Donovan, M. J. Owen, N. Craddock, M. Schwarz, H. Vedder, J. Kammerer-Ciernioch, A. Reif, J. Sasse, M. Bauer, M. Hautzinger, A. Wright, P. B. Mitchell, P. R. Schofield, G. W. Montgomery, S. E. Medland, S. D. Gordon, N. G. Martin, O. Gustafsson, O. Andreassen, S. Djurovic, E. Sigurdsson, S. Steinberg, H. Stefansson, K. Stefansson, L. Kapur-Pojskic, L. Oruc, F. Rivas, F. Mayoral, A. Chuchalin, G. Babadjanova, A. S. Tiganov, G. Pantelejeva, L. I. Abramova, M. Grigoroiu-Serbanescu, C. C. Diaconu, P. M. Czerski, J. Hauser, A. Zimmer, M. Lathrop, T. G. Schulze, T. F. Wienker, J. Schumacher, W. Maier, P. Propping, M. Rietschel, and M. M. Nothen (2011) Genome-wide association study identifies genetic variation in neurocan as a susceptibility factor for bipolar disorder. Am.J.Hum.Genet. 88:372-381.

 

Glas, J., J. Seiderer, C. Tillack, S. Pfennig, F. Beigel, M. Jurgens, T. Olszak, R. P. Laubender, M. Weidinger, B. Muller-Myhsok, B. Goke, T. Ochsenkuhn, P. Lohse, J. Diegelmann, D. Czamara, and S. Brand (2010) The NOD2 single nucleotide polymorphisms rs2066843 and rs2076756 are novel and common Crohn's disease susceptibility gene variants. PLoS.One. 5:e14466.

 

Konig, I. R., J. Schumacher, P. Hoffmann, A. Kleensang, K. U. Ludwig, T. Grimm, N. Neuhoff, M. Preis, D. Roeske, A. Warnke, P. Propping, H. Remschmidt, M. M. Nothen, A. Ziegler, B. Muller-Myhsok, and G. Schulte-Korne (2011) Mapping for dyslexia and related cognitive trait loci provides strong evidence for further risk genes on chromosome 6p21. Am.J.Med.Genet.B Neuropsychiatr.Genet. 156B:36-43.

 

Kam-Thong, T., D. Czamara, K. Tsuda, K. Borgwardt, C. M. Lewis, A. Erhardt-Lehmann, B. Hemmer, P. Rieckmann, M. Daake, F. Weber, C. Wolf, A. Ziegler, B. Putz, F. Holsboer, B. Scholkopf, and B. Muller-Myhsok (2011) EPIBLASTER-fast exhaustive two-locus epistasis detection strategy using graphical processing units. Eur.J.Hum.Genet. 19:465-471.

 

Oexle, K., J. S. Ried, A. A. Hicks, T. Tanaka, C. Hayward, M. Bruegel, M. Gogele, P. Lichtner, B. Muller-Myhsok, A. Doring, T. Illig, C. Schwienbacher, C. Minelli, I. Pichler, G. M. Fiedler, J. Thiery, I. Rudan, A. F. Wright, H. Campbell, L. Ferrucci, S. Bandinelli, P. P. Pramstaller, H. E. Wichmann, C. Gieger, J. Winkelmann, and T. Meitinger (2011) Novel association to the proprotein convertase PCSK7 gene locus revealed by analysing soluble transferrin receptor (sTfR) levels. Hum.Mol.Genet. 20:1042-1047.

 

Glas, J., J. Seiderer, C. Tillack, E. Paschos, M. Wetzke, J. Diegelmann, D. Czamara, and S. Brand (2010) Functional SFTPD gene variants are not associated with susceptibility to inflammatory bowel disease in the German population. Inflamm.Bowel.Dis.17(6):1439-40.

 

Glas, J., J. Seiderer, D. Fischer, B. Tengler, S. Pfennig, M. Wetzke, F. Beigel, T. Olszak, M. Weidinger, B. Goke, T. Ochsenkuhn, M. Folwaczny, B. Muller-Myhsok, J. Diegelmann, D. Czamara, and S. Brand (2010) Pregnane X receptor (PXR/NR1I2) gene haplotypes modulate susceptibility to inflammatory bowel disease. Inflamm.Bowel.Dis.17(9):1917-24.

 

Czamara, D., J. Bruder, J. Becker, J. Bartling, P. Hoffmann, K. U. Ludwig, B. Muller-Myhsok, and G. Schulte-Korne (2011) Association of a rare variant with mismatch negativity in a region between KIAA0319 and DCDC2 in dyslexia. Behav.Genet. 41:110-119.

 

Trumbach, D., C. Graf, B. Putz, C. Kuhne, M. Panhuysen, P. Weber, F. Holsboer, W. Wurst, G. Welzl, and J. M. Deussing (2010) Deducing corticotropin-releasing hormone receptor type 1 signaling networks from gene expression data by usage of genetic algorithms and graphical Gaussian models. BMC.Syst.Biol. 19;4:159.:159.

 

Konig, I. R., J. Schumacher, P. Hoffmann, A. Kleensang, K. U. Ludwig, T. Grimm, N. Neuhoff, M. Preis, D. Roeske, A. Warnke, P. Propping, H. Remschmidt, M. M. Nothen, A. Ziegler, B. Muller-Myhsok, and G. Schulte-Korne (2010) Mapping for dyslexia and related cognitive trait loci provides strong evidence for further risk genes on chromosome 6p21. Am.J.Med.Genet.B Neuropsychiatr.Genet.156B(1):36-43.

 

Tsolakidou, A., L. Czibere, B. Putz, D. Trumbach, M. Panhuysen, J. M. Deussing, W. Wurst, I. Sillaber, R. Landgraf, F. Holsboer, and T. Rein (2010) Gene expression profiling in the stress control brain region hypothalamic paraventricular nucleus reveals a novel gene network including amyloid beta precursor protein. BMC.Genomics. 11:546.:546.

 

Nischwitz, S., S. Cepok, A. Kroner, C. Wolf, M. Knop, F. Muller-Sarnowski, H. Pfister, P. Rieckmann, B. Hemmer, M. Ising, M. Uhr, T. Bettecken, F. Holsboer, B. Muller-Myhsok, and F. Weber (2011) More CLEC16A gene variants associated with multiple sclerosis. Acta Neurol.Scand. 123:400-406.

 

Anttila, V., H. Stefansson, M. Kallela, U. Todt, G. M. Terwindt, M. S. Calafato, D. R. Nyholt, A. S. Dimas, T. Freilinger, B. Muller-Myhsok, V. Artto, M. Inouye, K. Alakurtti, M. A. Kaunisto, E. Hamalainen, V. B. de, A. H. Stam, C. M. Weller, A. Heinze, K. Heinze-Kuhn, I. Goebel, G. Borck, H. Gobel, S. Steinberg, C. Wolf, A. Bjornsson, G. Gudmundsson, M. Kirchmann, A. Hauge, T. Werge, J. Schoenen, J. G. Eriksson, K. Hagen, L. Stovner, H. E. Wichmann, T. Meitinger, M. Alexander, S. Moebus, S. Schreiber, Y. S. Aulchenko, M. M. Breteler, A. G. Uitterlinden, A. Hofman, C. M. van Duijn, P. Tikka-Kleemola, S. Vepsalainen, S. Lucae, F. Tozzi, P. Muglia, J. Barrett, J. Kaprio, M. Farkkila, L. Peltonen, K. Stefansson, J. A. Zwart, M. D. Ferrari, J. Olesen, M. Daly, M. Wessman, A. M. van den Maagdenberg, M. Dichgans, C. Kubisch, E. T. Dermitzakis, R. R. Frants, and A. Palotie (2010) Genome-wide association study of migraine implicates a common susceptibility variant on 8q22.1. Nat.Genet. 42:869-873.

 

Glas, J., J. Seiderer, C. Markus, S. Pfennig, M. Wetzke, E. Paschos, B. Goke, T. Ochsenkuhn, B. Muller-Myhsok, J. Diegelmann, D. Roeske, and S. Brand (2011) Role of PPARG gene variants in inflammatory bowel disease. Inflamm.Bowel.Dis. 17:1057-1058.

 

Rietschel, M., M. Mattheisen, J. Frank, J. Treutlein, F. Degenhardt, R. Breuer, M. Steffens, D. Mier, C. Esslinger, H. Walter, P. Kirsch, S. Erk, K. Schnell, S. Herms, H. E. Wichmann, S. Schreiber, K. H. Jockel, J. Strohmaier, D. Roeske, B. Haenisch, M. Gross, S. Hoefels, S. Lucae, E. B. Binder, T. F. Wienker, T. G. Schulze, C. Schmal, A. Zimmer, D. Juraeva, B. Brors, T. Bettecken, A. Meyer-Lindenberg, B. Muller-Myhsok, W. Maier, M. M. Nothen, and S. Cichon (2010) Genome-wide association-, replication-, and neuroimaging study implicates HOMER1 in the etiology of major depression. Biol.Psychiatry. 68:578-585.

 

Nischwitz, S., S. Cepok, A. Kroner, C. Wolf, M. Knop, F. Muller-Sarnowski, H. Pfister, D. Roeske, P. Rieckmann, B. Hemmer, M. Ising, M. Uhr, T. Bettecken, F. Holsboer, B. Muller-Myhsok, and F. Weber (2010) Evidence for VAV2 and ZNF433 as susceptibility genes for multiple sclerosis. J.Neuroimmunol. 227:162-166.

 

Glas, J., J. Seiderer, M. Nagy, C. Fries, F. Beigel, M. Weidinger, S. Pfennig, W. Klein, J. T. Epplen, P. Lohse, M. Folwaczny, B. Goke, T. Ochsenkuhn, J. Diegelmann, B. Muller-Myhsok, D. Roeske, and S. Brand (2010) Evidence for STAT4 as a common autoimmune gene: rs7574865 is associated with colonic Crohn's disease and early disease onset. PLoS.One. 5:e10373.

 

Meindl, A., H. Hellebrand, C. Wiek, V. Erven, B. Wappenschmidt, D. Niederacher, M. Freund, P. Lichtner, L. Hartmann, H. Schaal, J. Ramser, E. Honisch, C. Kubisch, H. E. Wichmann, K. Kast, H. Deissler, C. Engel, B. Muller-Myhsok, K. Neveling, M. Kiechle, C. G. Mathew, D. Schindler, R. K. Schmutzler, and H. Hanenberg (2010) Germline mutations in breast and ovarian cancer pedigrees establish RAD51C as a human cancer susceptibility gene. Nat.Genet. 42:410-414.

 

Erhardt, A., L. Czibere, D. Roeske, S. Lucae, P. G. Unschuld, S. Ripke, M. Specht, M. A. Kohli, S. Kloiber, M. Ising, A. Heck, H. Pfister, P. Zimmermann, R. Lieb, B. Putz, M. Uhr, P. Weber, J. M. Deussing, M. Gonik, M. Bunck, M. S. Kebler, E. Frank, C. Hohoff, K. Domschke, P. Krakowitzky, W. Maier, B. Bandelow, C. Jacob, J. Deckert, S. Schreiber, J. Strohmaier, M. Nothen, S. Cichon, M. Rietschel, T. Bettecken, M. E. Keck, R. Landgraf, B. Muller-Myhsok, F. Holsboer, and E. B. Binder (2011) TMEM132D, a new candidate for anxiety phenotypes: evidence from human and mouse studies. Mol.Psychiatry. 16:647-663.

 

Unschuld, P. G., M. Ising, D. Roeske, A. Erhardt, M. Specht, S. Kloiber, M. Uhr, B. Muller-Myhsok, F. Holsboer, and E. B. Binder (2010) Gender-specific association of galanin polymorphisms with HPA-axis dysregulation, symptom severity, and antidepressant treatment response. Neuropsychopharmacology. 35:1583-1592.

 

Kleensang, A., D. Franke, A. Alcais, L. Abel, B. Muller-Myhsok, and A. Ziegler (2010) An extensive comparison of quantitative trait Loci mapping methods. Hum.Hered. 69:202-211.

 

Allebrandt, K. V., M. Teder-Laving, M. Akyol, I. Pichler, B. Muller-Myhsok, P. Pramstaller, M. Merrow, T. Meitinger, A. Metspalu, and T. Roenneberg (2010) CLOCK gene variants associate with sleep duration in two independent populations. Biol.Psychiatry. 67:1040-1047.

 

Kohli, M. A., D. Salyakina, A. Pfennig, S. Lucae, S. Horstmann, A. Menke, S. Kloiber, J. Hennings, B. B. Bradley, K. J. Ressler, M. Uhr, B. Muller-Myhsok, F. Holsboer, and E. B. Binder (2010) Association of genetic variants in the neurotrophic receptor-encoding gene NTRK2 and a lifetime history of suicide attempts in depressed patients. Arch.Gen.Psychiatry. 67:348-359.

 

Wolf, C., E. Gramer, B. Muller-Myhsok, F. Pasutto, B. Wissinger, and N. Weisschuh (2010) Mitochondrial haplogroup U is associated with a reduced risk to develop exfoliation glaucoma in the German population. BMC.Genet. 11:8.:8.

 

Pfeufer, A., N. C. van, K. D. Marciante, D. E. Arking, M. G. Larson, A. V. Smith, K. V. Tarasov, M. Muller, N. Sotoodehnia, M. F. Sinner, G. C. Verwoert, M. Li, W. H. Kao, A. Kottgen, J. Coresh, J. C. Bis, B. M. Psaty, K. Rice, J. I. Rotter, F. Rivadeneira, A. Hofman, J. A. Kors, B. H. Stricker, A. G. Uitterlinden, C. M. van Duijn, B. M. Beckmann, W. Sauter, C. Gieger, S. A. Lubitz, C. Newton-Cheh, T. J. Wang, J. W. Magnani, R. B. Schnabel, M. K. Chung, J. Barnard, J. D. Smith, D. R. Van Wagoner, R. S. Vasan, T. Aspelund, G. Eiriksdottir, T. B. Harris, L. J. Launer, S. S. Najjar, E. Lakatta, D. Schlessinger, M. Uda, G. R. Abecasis, B. Muller-Myhsok, G. B. Ehret, E. Boerwinkle, A. Chakravarti, E. Z. Soliman, K. L. Lunetta, S. Perz, H. E. Wichmann, T. Meitinger, D. Levy, V. Gudnason, P. T. Ellinor, S. Sanna, S. Kaab, J. C. Witteman, A. Alonso, E. J. Benjamin, and S. R. Heckbert (2010) Genome-wide association study of PR interval. Nat.Genet. 42:153-159.

 

Horstmann, S., S. Lucae, A. Menke, J. M. Hennings, M. Ising, D. Roeske, B. Muller-Myhsok, F. Holsboer, and E. B. Binder (2010) Polymorphisms in GRIK4, HTR2A, and FKBP5 show interactive effects in predicting remission to antidepressant treatment. Neuropsychopharmacology. 35:727-740.

 

Hemminki, K., B. Muller-Myhsok, P. Lichtner, C. Engel, B. Chen, B. Burwinkel, A. Forsti, C. Sutter, B. Wappenschmidt, H. Hellebrand, T. Illig, N. Arnold, D. Niederacher, B. Dworniczak, H. Deissler, K. Kast, D. Gadzicki, T. Meitinger, H. E. Wichmann, M. Kiechle, C. R. Bartram, R. K. Schmutzler, and A. Meindl (2010) Low-risk variants FGFR2, TNRC9 and LSP1 in German familial breast cancer patients. Int.J.Cancer. 126:2858-2862.

 

Roeske, D., K. U. Ludwig, N. Neuhoff, J. Becker, J. Bartling, J. Bruder, F. F. Brockschmidt, A. Warnke, H. Remschmidt, P. Hoffmann, B. Muller-Myhsok, M. M. Nothen, and G. Schulte-Korne (2011) First genome-wide association scan on neurophysiological endophenotypes points to trans-regulation effects on SLC2A3 in dyslexic children. Mol.Psychiatry. 16:97-107.

 

Lucae, S., M. Ising, S. Horstmann, B. T. Baune, V. Arolt, B. Muller-Myhsok, F. Holsboer, and K. Domschke (2010) HTR2A gene variation is involved in antidepressant treatment response. Eur.Neuropsychopharmacol. 20:65-68.

 

Wolf, C., E. Gramer, B. Muller-Myhsok, F. Pasutto, E. Reinthal, B. Wissinger, and N. Weisschuh (2009) Evaluation of nine candidate genes in patients with normal tension glaucoma: a case control study. BMC.Med.Genet. 10:91.:91.

 

Ludwig, K. U., M. Mattheisen, T. W. Muhleisen, D. Roeske, C. Schmal, R. Breuer, G. Schulte-Korne, B. Muller-Myhsok, M. M. Nothen, P. Hoffmann, M. Rietschel, and S. Cichon (2009) Supporting evidence for LRRTM1 imprinting effects in schizophrenia. Mol.Psychiatry. 14:743-745.

 

Ising M, Lucae S, Binder EB, Bettecken T, Uhr M, Ripke S, Kohli M, Hennings J, Horstmann  S, Klober S, Menke A, Bondy B, Rupprecht R, Domschke K, Baune B, Arolt V, Rush J, Holsboer F, Müller-Myhsok B. (2009) A genome-wide study points to multiple loci predicting anti-depressant treatment outcome in depression. Arch Gen Psychiatry 66(9):966-975.

 

Ludwig KU, Roeske D, Herms S, Schumacher J, Warnke A, Plume E, Neuhoff N, Bruder J, Remschmidt H, Schulte-Körne G, Müller-Myhsok B, Nöthen MM, Hoffmann P. (2009) Variation in GRIN2B contributes to weak performance in verbal short-term memory in children with dyslexia. Am J Med Genet B Neuropsychiatr Genet.153B(2):503-11.

 

Heck A, Lieb R, Ellgas A, Pfister H, Lucae S, Roeske D, Pütz B, Müller-Myhsok B, Uhr M, Holsboer F, Ising M (2009) Investigation of 17 candidate genes for personality traits confirms effects of the HTR2A gene on novelty seeking. Genes Brain Behav. 8:464-72.

 

Gschwendtner A, Bevan S, Cole JW, Plourde A, Matarin M, Ross-Adams H, Meitinger T, Wichmann E, Mitchell BD, Furie K, Slowik A, Rich SS, Syme PD, MacLeod MJ, Meschia JF, Rosand J, Kittner SJ, Markus HS, Müller-Myhsok B, Dichgans M; International Stroke Genetics Consortium (2009) Sequence variants on chromosome 9p21.3 confer risk for atherosclerotic stroke. Ann Neurol. 2009 65:531-9.

 

Török HP, Glas J, Endres I, Tonenchi L, Teshome MY, Wetzke M, Klein W, Lohse P, Ochsenkühn T, Folwaczny M, Göke B, Folwaczny C, Müller-Myhsok B, Brand S (2009) Epistasis between Toll-like receptor-9 polymorphisms and variants in NOD2 and IL23R modulates susceptibility to Crohn's disease. Am J Gastroenterol. 2009 104:1723-33

 

Liebl C, Panhuysen M, Pütz B, Trümbach D, Wurst W, Deussing JM, Müller MB, Schmidt MV (2009) Gene expression profiling following maternal deprivation: involvement of the brain Renin-Angiotensin system. Front Mol Neurosci 2:1.

 

Glas J, Stallhofer J, Ripke S, Wetzke M, Pfennig S, Klein W, Epplen JT, Griga T, Schiemann U, Lacher M, Koletzko S, Folwaczny M, Lohse P, Göke B, Ochsenkühn T, Müller-Myhsok B, Brand S (2009) Novel genetic risk markers for ulcerative colitis in the IL2/IL21 region are in epistasis with IL23R and suggest a common genetic background for ulcerative colitis and celiac disease. Am J Gastroenterol. 2009 104:1737-44.

 

Yehuda R, Cai G, Golier JA, Sarapas C, Galea S, Ising M, Rein T, Schmeidler J, Müller-Myhsok B, Holsboer F, Buxbaum JD (2009). Gene Expression Patterns Associated with Posttraumatic Stress Disorder Following Exposure to the World Trade Center Attacks Biol Psychiatry. 66(7):708-11.

 

Hoffmann K, Planitz C, Rüschendorf F, Müller-Myhsok B, Stassen HH, Lucke B, Mattheisen M, Stumvoll M, Bochmann R, Zschornack M, Wienker TF, Nürnberg P, Reis A, Luft FC, Lindner TH (2009) A novel locus for arterial hypertension on chromosome 1p36 maps to a metabolic syndrome trait cluster in the Sorbs, a Slavic population isolate in Germany. J Hypertens. 27:983-90.

 

Heck, A., Lieb, R., Ellgas, A., Pfister, H., Lucae, S., Erhardt, A., Himmerich, H., Horstmann, S., Kloiber, S., Ripke, S., Muller-Myhsok, B., Bettecken, T., Uhr, M., Holsboer, F., and Ising, M. (2009) Polymorphisms in the angiotensin-converting enzyme gene region predict coping styles in healthy adults and depressed patients. Am. J. Med. Genet. B Neuropsychiatr. Genet. 150B:104-14

 

Wolf C, Gramer E, Müller-Myhsok B, Pasutto F, Gramer G, Wissinger B, Weisschuh N (2009) Lysyl Oxidase-like 1 Gene Polymorphisms in German Patients With Normal Tension Glaucoma, Pigmentary Glaucoma and Exfoliation Glaucoma. J Glaucoma. 19(2):136-41.

 

Bunck M, Czibere L, Horvath C, Graf C, Frank E, Kessler MS, Murgatroyd C, Müller-Myhsok B, Gonik M, Weber P, Pütz B, Muigg P, Panhuysen M, Singewald N, Bettecken T, Deussing JM, Holsboer F, Spengler D, Landgraf R (2009) A hypomorphic vasopressin allele prevents anxiety-related behavior. PLoS One. 4:e5129.

 

Pfeufer A, Sanna S, Arking DE, Müller M, Gateva V, Fuchsberger C, Ehret GB, Orrú M, Pattaro C, Köttgen A, Perz S, Usala G, Barbalic M, Li M, Pütz B, Scuteri A, Prineas RJ, Sinner MF, Gieger C, Najjar SS, Kao WH, Mühleisen TW, Dei M, Happle C, Möhlenkamp S, Crisponi L, Erbel R, Jöckel KH, Naitza S, Steinbeck G, Marroni F, Hicks AA, Lakatta E, Müller-Myhsok B, Pramstaller PP, Wichmann HE, Schlessinger D, Boerwinkle E, Meitinger T, Uda M, Coresh J, Kääb S, Abecasis GR, Chakravarti A (2009) Common variants at ten loci modulate the QT interval duration in the QTSCD Study. Nat Genet. 41:407-14

 

Kemlink D, Polo O, Frauscher B, Gschliesser V, Högl B, Poewe W, Vodicka P, Vavrova J, Sonka K, Nevsimalova S, Schormair B, Lichtner P, Silander K, Peltonen L, Gieger C, Wichmann HE, Zimprich A, Roeske D, Müller-Myhsok B, Meitinger T, Winkelmann J (2009) Replication of restless legs syndrome loci in three European populations. J Med Genet. 46:315-8

 

Glas J, Seiderer J, Pasciuto G, Tillack C, Diegelmann J, Pfennig S, Konrad A, Schmechel S, Wetzke M, Török HP, Stallhofer J, Jürgens M, Griga T, Klein W, Epplen JT, Schiemann U, Mussack T, Lohse P, Göke B, Ochsenkühn T, Folwaczny M, Müller-Myhsok B, Brand S(2009) rs224136 on chromosome 10q21.1 and variants in PHOX2B, NCF4, and FAM92B are not major genetic risk factors for susceptibility to Crohn's disease in the German population. Am J Gastroenterol. 104:665-72.

 

Dahdouh F, Anthoni H, Tapia-Páez I, Peyrard-Janvid M, Schulte-Körne G, Warnke A, Remschmidt H, Ziegler A, Kere J, Müller-Myhsok B, Nöthen MM, Schumacher J, Zucchell (2009) M. Further evidence for DYX1C1 as a susceptibility factor for dyslex Psychiatr Genet. 19(2):59-63.

 

Unschuld PG, Ising M, Specht M, Erhardt A, Ripke S, Heck A, Kloiber S, Straub V, Brueckl T, Müller-Myhsok B, Holsboer F, Binder EB (2009) Polymorphisms in the GAD2 gene-region are associated with susceptibility for unipolar depression and with a risk factor for anxiety disorders. Am J Med Genet B Neuropsychiatr Genet.150B(8):1100-9.

 

Freilinger T, Bevan S, Ripke S, Gschwendtner A, Lichtner P, Müller-Myhsok B, Wichmann HE, Markus HS, Meitinger T, Dichgans M (2009) Genetic variation in the lymphotoxin-alpha pathway and the risk of ischemic stroke in European populations. Stroke. 40:970-2.

 

Ditzen C, Varadarajulu J, Czibere L, Gonik M, Targosz BS, Hambsch B, Bettecken T, Keßler MS, Frank E, Bunck M, Teplytska L, Erhardt A, Holsboer F, Müller-Myhsok B, Landgraf R, Turck CW (2009) Proteomic-based genotyping in a mouse model of trait anxiety exposes disease-relevant pathways. Mol Psychiatry. 15(7):702-11.

 

Kloiber S, Kohli MA, Brueckl T, Ripke S, Ising M, Uhr M, Menke A, Unschuld PG, Horstmann S, Salyakina D, Muller-Myhsok B, Binder EB, Holsboer F, Lucae S (2009) Variations in tryptophan hydroxylase 2 linked to decreased serotonergic activity are associated with elevated risk for metabolic syndrome in depression. Mol Psychiatry 15:736-747.

 

Muglia P, Tozzi F, Galwey NW, Francks C, Upmanyu R, Kong XQ, Antoniades A, Domenici E, Perry J, Rothen S, Vandeleur CL, Mooser V, Waeber G, Vollenweider P, Preisig M, Lucae S, Müller-Myhsok B, Holsboer F, Middleton LT, Roses AD (2008) Genome-wide association study of recurrent major depressive disorder in two European case-control cohorts. Mol Psychiatry 15:589-601.

 

Gusareva ES, Havelková H, Blazková H, Kosarová M, Kucera P, Král V, Salyakina D, Müller-Myhsok B, Lipoldová M (2009) Mouse to human comparative genetics reveals a novel immunoglobulin E-controlling locus on Hsa8q12. Immunogenetics 61:15-25

 

Ludwig KU, Schumacher J, Schulte-Körne G, König IR, Warnke A, Plume E, Anthoni H, Peyrard-Janvid M, Meng H, Ziegler A, Remschmidt H, Kere J, Gruen JR, Müller-Myhsok B, Nöthen MM, Hoffmann P (2008) Investigation of the DCDC2 intron 2 deletion/compound short tandem repeat polymorphism in a large German dyslexia sample  Psychiatr Genet. 18:310-2.

 

Ludwig, K. U., Roeske, D., Schumacher, J., Schulte-Korne, G., Konig, I. R., Warnke, A., Plume, E., Ziegler, A., Remschmidt, H., Muller-Myhsok, B., Nothen, M. M., and Hoffmann, P. (2008) Investigation of interaction between DCDC2 and KIAA0319 in a large German dyslexia sample. J. Neural Transm 115:1587-9

 

Heck, A., Lieb, R., Unschuld, P. G., Ellgas, A., Pfister, H., Lucae, S., Erhardt, A., Himmerich, H., Horstmann, S., Kloiber, S., Ripke, S., Muller-Myhsok, B., Bettecken, T., Uhr, M., Holsboer, F., and Ising, M. (2008) Evidence for associations between PDE4D polymorphisms and a subtype of neuroticism. Mol. Psychiatry 13: 831-832

 

Ising, M., Depping, A. M., Siebertz, A., Lucae, S., Unschuld, P. G., Kloiber, S., Horstmann, S., Uhr, M., Muller-Myhsok, B., and Holsboer, F. (2008) Polymorphisms in the FKBP5 gene region modulate recovery from psychosocial stress in healthy controls. Eur. J. Neurosci. 28: 389-398

 

Schormair, B., Kemlink, D., Roeske, D., Eckstein, G., Xiong, L., Lichtner, P., Ripke, S., Trenkwalder, C., Zimprich, A., Stiasny-Kolster, K., Oertel, W., Bachmann, C. G., Paulus, W., Hogl, B., Frauscher, B., Gschliesser, V., Poewe, W., Peglau, I., Vodicka, P., Vavrova, J., Sonka, K., Nevsimalova, S., Montplaisir, J., Turecki, G., Rouleau, G., Gieger, C., Illig, T., Wichmann, H. E., Holsboer, F., Muller-Myhsok, B., Meitinger, T., and Winkelmann, J. (2008) PTPRD (protein tyrosine phosphatase receptor type delta) is associated with restless legs syndrome. Nat. Genet. 40: 946-948

 

Menke, A., Lucae, S., Kloiber, S., Horstmann, S., Bettecken, T., Uhr, M., Ripke, S., Ising, M., Muller-Myhsok, B., Holsboer, F., and Binder, E. B. (2008) Genetic markers within glutamate receptors associated with antidepressant treatment-emergent suicidal ideation. Am. J. Psychiatry 165: 917-918

 

Kemlink, D., G. Plazzi, R. Vetrugno, F. Provini, O. Polo, K. Stiasny-Kolster, W. Oertel, S. Nevsimalova, K. Sonka, B. Hogl, B. Frauscher, G. M. Hadjigeorgiou, P. P. Pramstaller, P. Lichtner, T. Meitinger, B. Muller-Myshok, J. Winkelmann, and P. Montagna (2008) Suggestive evidence for linkage for restless legs syndrome on chromosome 19p13. Neurogenetics. 9:75-82.

 

International Multiple Sclerosis Genetics Consortium (IMSGC). (2008) Refining genetic associations in multiple sclerosis. Lancet Neurol. 7: 567-569

 

Glas, J., Beynon, V., Bachstein, B., Steckenbiller, J., Manolis, V., Euba, A., Muller-Myhsok, B., and Folwaczny, M. (2008) Increased plasma concentration of surfactant protein D in chronic periodontitis independent of SFTPD genotype: potential role as a biomarker. Tissue Antigens 72: 21-28

 

Schumacher, J., Konig, I. R., Schroder, T., Duell, M., Plume, E., Propping, P., Warnke, A., Libertus, C., Ziegler, A., Muller-Myhsok, B., Schulte-Korne, G., and Nothen, M. M. (2008) Further evidence for a susceptibility locus contributing to reading disability on chromosome 15q15-q21. Psychiatr. Genet. 18: 137-142

 

Keck, M. E., Kern, N., Erhardt, A., Unschuld, P. G., Ising, M., Salyakina, D., Muller, M. B., Knorr, C. C., Lieb, R., Hohoff, C., Krakowitzky, P., Maier, W., Bandelow, B., Fritze, J., Deckert, J., Holsboer, F., Muller-Myhsok, B., and Binder, E. B. (2008) Combined effects of exonic polymorphisms in CRHR1 and AVPR1B genes in a case/control study for panic disorder. Am. J. Med. Genet. B Neuropsychiatr. Genet. 147B: 1196-1204

 

Sillaber I, Panhuysen M, Henniger MS, Ohl F, Kühne C, Pütz B, Pohl T, Deussing JM, Paez-Pereda M, Holsboer F (2008) Profiling of behavioral changes and hippocampal gene expression in mice chronically treated with the SSRI paroxetine. Psychopharmacology (Berlin) 200:557-72

 

Tsolakidou A, Trümbach D, Panhuysen M, Pütz B, Deussing J, Wurst W, Sillaber I, Holsboer F, Rein T.(2008) Acute stress regulation of neuroplasticity genes in mouse hippocampus CA3 area--possible novel signalling pathways. Mol Cell Neurosci. 38 :444-52. 

 

Weber, F., Fontaine, B., Cournu-Rebeix, I., Kroner, A., Knop, M., Lutz, S., Muller-Sarnowski, F., Uhr, M., Bettecken, T., Kohli, M., Ripke, S., Ising, M., Rieckmann, P., Brassat, D., Semana, G., Babron, M. C., Mrejen, S., Gout, C., Lyon-Caen, O., Yaouanq, J., Edan, G., Clanet, M., Holsboer, F., Clerget-Darpoux, F., and Muller-Myhsok, B. (2008) IL2RA and IL7RA genes confer susceptibility for multiple sclerosis in two independent European populations. Genes Immun. 9: 259-263

 

Gschwendtner, A., Ripke, S., Freilinger, T., Lichtner, P., Muller-Myhsok, B., Wichmann, H. E., Meitinger, T., and Dichgans, M. (2008) Genetic variation in soluble epoxide hydrolase (EPHX2) is associated with an increased risk of ischemic stroke in white Europeans. Stroke 39: 1593-1596

 

Winkelmann, J. and Muller-Myhsok, B. (2008) Genetics of restless legs syndrome: a burning urge to move. Neurology  70: 664-665

 

Erhardt, A., Lucae, S., Kern, N., Unschuld, P. G., Ising, M., Lieb, R., Uhr, M., Hohoff, C., Deckert, J., Bandelow, B., Maier, W., Binder, E. B., Muller-Myhsok, B., Keck, M. E., and Holsboer, F. (2008) Association of polymorphisms in the angiotensin-converting enzyme gene with syndromal panic attacks. Mol. Psychiatry 13:242-243

 

Freilinger, T., Bohe, M., Wegener, B., Muller-Myhsok, B., Dichgans, M., and Knoblauch, H. (2008) Expansion of the phenotypic spectrum of the CACNA1A T666M mutation: a family with familial hemiplegic migraine type 1, cerebellar atrophy and mental retardation. Cephalalgia 28: 403-407

 

Seiderer, J., Dambacher, J., Leistner, D., Tillack, C., Glas, J., Niess, J. H., Pfennig, S., Jurgens, M., Muller-Myhsok, B., Goke, B., Ochsenkuhn, T., Lohse, P., Reinecker, H. C., and Brand, S. (2008) Genotype-phenotype analysis of the CXCL16 p.Ala181Val polymorphism in inflammatory bowel disease. Clin. Immunol. 127:49-55

 

Uhr, M., Tontsch, A., Namendorf, C., Ripke, S., Lucae, S., Ising, M., Dose, T., Ebinger, M., Rosenhagen, M., Kohli, M., Kloiber, S., Salyakina, D., Bettecken, T., Specht, M., Putz, B., Binder, E. B., Muller-Myhsok, B., and Holsboer, F. (2008) Polymorphisms in the drug transporter gene ABCB1 predict antidepressant treatment response in depression. Neuron 57: 203-209

 

Glas, J., Konrad, A., Schmechel, S., Dambacher, J., Seiderer, J., Schroff, F., Wetzke, M., Roeske, D., Torok, H. P., Tonenchi, L., Pfennig, S., Haller, D., Griga, T., Klein, W., Epplen, J. T., Folwaczny, C., Lohse, P., Goke, B., Ochsenkuhn, T., Mussack, T., Folwaczny, M., Muller-Myhsok, B., and Brand, S. (2008) The ATG16L1 gene variants rs2241879 and rs2241880 (T300A) are strongly associated with susceptibility to Crohn's disease in the German population. Am. J. Gastroenterol. 103: 682-691

 

Seiderer, J., Elben, I., Diegelmann, J., Glas, J., Stallhofer, J., Tillack, C., Pfennig, S., Jurgens, M., Schmechel, S., Konrad, A., Goke, B., Ochsenkuhn, T., Muller-Myhsok, B., Lohse, P., and Brand, S. (2008) Role of the novel Th17 cytokine IL-17F in inflammatory bowel disease (IBD): upregulated colonic IL-17F expression in active Crohn's disease and analysis of the IL17F p.His161Arg polymorphism in IBD. Inflamm. Bowel. Dis. 14:437-445

 

Winkelmann, J., Lichtner, P., Schormair, B., Uhr, M., Hauk, S., Stiasny-Kolster, K., Trenkwalder, C., Paulus, W., Peglau, I., Eisensehr, I., Illig, T., Wichmann, H. E., Pfister, H., Golic, J., Bettecken, T., Putz, B., Holsboer, F., Meitinger, T., and Muller-Myhsok, B. (2008) Variants in the neuronal nitric oxide synthase (nNOS, NOS1) gene are associated with restless legs syndrome. Mov Disord. 23: 350-358

 

Glas, J., Seiderer, J., Wetzke, M., Konrad, A., Torok, H. P., Schmechel, S., Tonenchi, L., Grassl, C., Dambacher, J., Pfennig, S., Maier, K., Griga, T., Klein, W., Epplen, J. T., Schiemann, U., Folwaczny, C., Lohse, P., Goke, B., Ochsenkuhn, T., Muller-Myhsok, B., Folwaczny, M., Mussack, T., and Brand, S. (2007) rs1004819 is the main disease-associated IL23R variant in German Crohn's disease patients: combined analysis of IL23R, CARD15, and OCTN1/2 variants. PLoS. ONE. 2, e819

 

Browning, B. L., Annese, V., Barclay, M. L., Bingham, S. A., Brand, S., Buning, C., Castro, M., Cucchiara, S., Dallapiccola, B., Drummond, H., Ferguson, L. R., Ferraris, A., Fisher, S. A., Gearry, R. B., Glas, J., Henckaerts, L., Huebner, C., Knafelz, D., Lakatos, L., Lakatos, P. L., Latiano, A., Liu, X., Mathew, C., Muller-Myhsok, B., Newman, W. G., Nimmo, E. R., Noble, C. L., Palmieri, O., Parkes, M., Petermann, I., Rutgeerts, P., Satsangi, J., Shelling, A. N., Siminovitch, K. A., Torok, H. P., Tremelling, M., Vermeire, S., Valvano, M. R., and Witt, H. (2008) Gender-stratified analysis of DLG5 R30Q in 4707 patients with Crohn disease and 4973 controls from 12 Caucasian cohorts. J. Med. Genet. 45:36-42

 

Unschuld, P. G., Ising, M., Erhardt, A., Lucae, S., Kohli, M., Kloiber, S., Salyakina, D., Thoeringer, C. K., Kern, N., Lieb, R., Uhr, M., Binder, E. B., Muller-Myhsok, B., Holsboer, F., and Keck, M. E. (2008) Polymorphisms in the galanin gene are associated with symptom-severity in female patients suffering from panic disorder. J. Affect. Disord. 105:177-184

 

Winkelmann, J., Schormair, B., Lichtner, P., Ripke, S., Xiong, L., Jalilzadeh, S., Fulda, S., Putz, B., Eckstein, G., Hauk, S., Trenkwalder, C., Zimprich, A., Stiasny-Kolster, K., Oertel, W., Bachmann, C. G., Paulus, W., Peglau, I., Eisensehr, I., Montplaisir, J., Turecki, G., Rouleau, G., Gieger, C., Illig, T., Wichmann, H. E., Holsboer, F., Muller-Myhsok, B., and Meitinger, T. (2007) Genome-wide association study of restless legs syndrome identifies common variants in three genomic regions. Nat. Genet. 39: 1000-1006

 

Rosenberger, A., Sharma, M., Muller-Myhsok, B., Gasser, T., and Bickeboller, H. (2007) Meta analysis of whole-genome linkage scans with data uncertainty: an application to Parkinson's disease. BMC. Genet. 8:44

 

Aulchenko YS, Ripke S, Isaacs A, van Duijn CM (2007) GenABEL: an R library for genome-wide association analysis. Bioinformatics 23:1294-6.

 

Kemlink, D., O. Polo, P. Montagna, F. Provini, K. Stiasny-Kolster, W. Oertel, W. A. de, S. Nevsimalova, K. Sonka, B. Hogl, B. Frauscher, W. Poewe, C. Trenkwalder, P. P. Pramstaller, L. Ferini-Strambi, M. Zucconi, E. Konofal, I. Arnulf, G. M. Hadjigeorgiou, S. Happe, C. Klein, A. Hiller, P. Lichtner, T. Meitinger, B. Muller-Myshok, and J. Winkelmann (2007) Family-based association study of the restless legs syndrome loci 2 and 3 in a European population. Mov Disord. 22:207-212.

 

Unschuld, P. G., Ising, M., Erhardt, A., Lucae, S., Kloiber, S., Kohli, M., Salyakina, D., Welt, T., Kern, N., Lieb, R., Uhr, M., Binder, E. B., Muller-Myhsok, B., Holsboer, F., and Keck, M. E. (2007) Polymorphisms in the serotonin receptor gene HTR2A are associated with quantitative traits in panic disorder. Am. J. Med. Genet. B Neuropsychiatr. Genet. 144B: 424-429

 

Deussing JM, Kühne C, Pütz B, Panhuysen M, Breu J, Stenzel-Poore MP, Holsboer F, Wurst W (2007) Expression profiling identifies the CRH/CRH-R1 system as a modulator of neurovascular gene activity. J Cereb Blood Flow Metab 27:1476-95

 

Anthoni, H., Zucchelli, M., Matsson, H., Muller-Myhsok, B., Fransson, I., Schumacher, J., Massinen, S., Onkamo, P., Warnke, A., Griesemann, H., Hoffmann, P., Nopola-Hemmi, J., Lyytinen, H., Schulte-Korne, G., Kere, J., Nothen, M. M., and Peyrard-Janvid, M. (2007) A locus on 2p12 containing the co-regulated MRPL19 and C2ORF3 genes is associated to dyslexia. Hum. Mol. Genet. 16:667-677

 

Erhardt, A., Lucae, S., Unschuld, P. G., Ising, M., Kern, N., Salyakina, D., Lieb, R., Uhr, M., Binder, E. B., Keck, M. E., Muller-Myhsok, B., and Holsboer, F. (2007) Association of polymorphisms in P2RX7 and CaMKKb with anxiety disorders. J. Affect. Disord. 101: 159-168

 

Thoeringer, C. K., Binder, E. B., Salyakina, D., Erhardt, A., Ising, M., Unschuld, P. G., Kern, N., Lucae, S., Brueckl, T. M., Mueller, M. B., Fuchs, B., Puetz, B., Lieb, R., Uhr, M., Holsboer, F., Mueller-Myhsok, B., and Keck, M. E. (2007) Association of a Met88Val diazepam binding inhibitor (DBI) gene polymorphism and anxiety disorders with panic attacks. J. Psychiatr. Res. 41: 579-584

 

Graefe, S. E., Streichert, T., Budde, B. S., Nurnberg, P., Steeg, C., Muller-Myhsok, B., and Fleischer, B. (2006) Genes from Chagas susceptibility loci that are differentially expressed in T. cruzi-resistant mice are candidates accounting for impaired immunity. PLoS. ONE. 1: e57

 

Bender, A., Koch, W., Elstner, M., Schombacher, Y., Bender, J., Moeschl, M., Gekeler, F., Muller-Myhsok, B., Gasser, T., Tatsch, K., and Klopstock, T. (2006) Creatine supplementation in Parkinson disease: a placebo-controlled randomized pilot trial. Neurology 67:  1262-1264

 

Opherk, C., Peters, N., Holtmannspotter, M., Gschwendtner, A., Muller-Myhsok, B., and Dichgans, M. (2006) Heritability of MRI lesion volume in CADASIL: evidence for genetic modifiers. Stroke 37: 2684-2689

 

Baghai, T. C., Binder, E. B., Schule, C., Salyakina, D., Eser, D., Lucae, S., Zwanzger, P., Haberger, C., Zill, P., Ising, M., Deiml, T., Uhr, M., Illig, T., Wichmann, H. E., Modell, S., Nothdurfter, C., Holsboer, F., Muller-Myhsok, B., Moller, H. J., Rupprecht, R., and Bondy, B. (2006) Polymorphisms in the angiotensin-converting enzyme gene are associated with unipolar depression, ACE activity and hypercortisolism. Mol. Psychiatry 11:1003-1015

 

Liebetanz, K. M., Winkelmann, J., Trenkwalder, C., Putz, B., Dichgans, M., Gasser, T., and Muller-Myhsok, B. (2006) RLS3: fine-mapping of an autosomal dominant locus in a family with intrafamilial heterogeneity. Neurology 67:320-321

 

Lucae, S., Salyakina, D., Barden, N., Harvey, M., Gagne, B., Labbe, M., Binder, E. B., Uhr, M., Paez-Pereda, M., Sillaber, I., Ising, M., Bruckl, T., Lieb, R., Holsboer, F., and Muller-Myhsok, B. (2006) P2RX7, a gene coding for a purinergic ligand-gated ion channel, is associated with major depressive disorder. Hum. Mol. Genet. 15: 2438-2445

 

Glas, J., Torok, H. P., Tonenchi, L., Muller-Myhsok, B., Mussack, T., Wetzke, M., Klein, W., Epplen, J. T., Griga, T., Schiemann, U., Lohse, P., Seiderer, J., Schnitzler, F., Brand, S., Ochsenkuhn, T., Folwaczny, M., and Folwaczny, C. (2006) Role of the NFKB1 -94ins/delATTG promoter polymorphism in IBD and potential interactions with polymorphisms in the CARD15/NOD2, IKBL, and IL-1RN genes. Inflamm. Bowel. Dis. 12: 606-611

 

Barden, N., Harvey, M., Gagne, B., Shink, E., Tremblay, M., Raymond, C., Labbe, M., Villeneuve, A., Rochette, D., Bordeleau, L., Stadler, H., Holsboer, F., and Muller-Myhsok, B. (2006) Analysis of single nucleotide polymorphisms in genes in the chromosome 12Q24.31 region points to P2RX7 as a susceptibility gene to bipolar affective disorder. Am. J. Med. Genet. B Neuropsychiatr. Genet. 141B:374-382.

 

Erhardt, A., M. Ising, P. G. Unschuld, N. Kern, S. Lucae, B. Putz, M. Uhr, E. B. Binder, F. Holsboer, and M. E. Keck (2006) Regulation of the hypothalamic-pituitary-adrenocortical system in patients with panic disorder. Neuropsychopharmacology. 31:2515-2522.

 

van Rossum EF, Binder EB, Majer M, Koper JW, Ising M, Modell S, Salyakina D, Lamberts SW, Holsboer F. (2006) Polymorphisms of the glucocorticoid receptor gene and major depression. Biol Psychiatry. 59:681-8.

 

Sharma, M., Mueller, J. C., Zimprich, A., Lichtner, P., Hofer, A., Leitner, P., Maass, S., Berg, D., Durr, A., Bonifati, V., De, M. G., Oostra, B., Brice, A., Wood, N. W., Muller-Myhsok, B., and Gasser, T. (2006) The sepiapterin reductase gene region reveals association in the PARK3 locus: analysis of familial and sporadic Parkinson's disease in European populations. J. Med. Genet. 43: 557-562.

 

Winkelmann, J., Lichtner, P., Putz, B., Trenkwalder, C., Hauk, S., Meitinger, T., Strom, T., and Muller-Myhsok, B. (2006) Evidence for further genetic locus heterogeneity and confirmation of RLS-1 in restless legs syndrome. Mov Disord. 21, 28-33

 

Glas, J., Torok, H. P., Tonenchi, L., Kapser, J., Schiemann, U., Muller-Myhsok, B., Folwaczny, M., and Folwaczny, C. (2005) Association of polymorphisms in the interleukin-18 gene in patients with Crohn's disease depending on the CARD15/NOD2 genotype. Inflamm. Bowel. Dis. 11, 1031-1037

 

Leal, S. M., Yan, K., and Muller-Myhsok, B. (2005) SimPed: a simulation program to generate haplotype and genotype data for pedigree structures. Hum. Hered. 60, 119-122

 

Salyakina, D., Seaman, S. R., Browning, B. L., Dudbridge, F., and Muller-Myhsok, B. (2005) Evaluation of Nyholt's procedure for multiple testing correction. Hum. Hered. 60, 19-25

 

Muller-Myhsok B. (2005) The usefulness of single nucleotide polymorphisms (SNPs) for genetic epidemiological investigation of complex psychiatric diseases. Prog Neuropsychopharmacol Biol Psychiatry 29(6):1017-20

 

Torok HP, Glas J, Tonenchi L, Lohse P, Muller-Myhsok B, Limbersky O, Neugebauer C, Schnitzler F, Seiderer J, Tillack C, Brand S, Brunnler G, Jagiello P, Epplen JT, Griga T, Klein W, Schiemann U, Folwaczny M, Ochsenkuhn T, Folwaczny C. (2005) Polymorphisms in the DLG5 and OCTN cation transporter genes in Crohn's disease. Gut. 54(10):1421-1427.

 

Klopstock T, Elstner M, Lucking CB, Muller-Myhsok B, Gasser T, Botz E, Lichtner P, Hortnagel K. (2005) Mutations in the pantothenate kinase gene PANK2 are not associated with Parkinson disease. Neurosci Lett. 379(3):195-8.

 

Ziegler A, König IR, Deimel W, Plume E, Nöthen MM, Propping P, Kleensang A, Müller-Myhsok B, Warnke A, Remschmidt H, Schulte-Körne G (2005) Developmental dyslexia – recurrence risk estimates from a German bi-center study using the single proband sib pair design. Hum Hered. 59(3):136-43.

 

Seaman SR, Müller-Myhsok B (2005) Rapid Simulation of P Values for Product Methods and Multiple-Testing Adjustment in Association Studies. Am J Hum Genet. 76:399-408.

 

Prestel J, Sharma M, Leitner P, Zimprich A, Vaughan JR, Dürr A, Bonifati V, de Michele G, Hanagasi HA, Farrer M, Hofer A, Asmus F, Volpe G, Meco G, Brice A, Wood NW, Müller-Myhsok B, Gasser T.: The European Consortium on Genetic Susceptibility in Parkionson's Disease (GSPD) (2005). PARK11 is not linked with Parkinson's disease in European families. Eur J Hum Genet. 13:193-197.

 

Asmus F, Schoenian S, Lichtner P, Munz M, Mayer P, Müller-Myhsok B, Zimprich A, Remschmidt H, Hebebrand J, Bandmann O, Gasser T (2005) Epsilon-Sarcoglycan (SGCE) is not involved in sporadic Gilles de la Tourette syndrome. Neurogenetics 6:55-56.

 

Brattig N, Timmann C, Abraha R, Lepping B, Müller-Myhsok B, Horstmann RD (2005) Relevance of ex-vivo blood lymphocyte assay for in-vivo lymphocyte function. Clin Exp Immun. 139:127-131.

 

Kromer, S. A., M. S. Kessler, D. Milfay, I. N. Birg, M. Bunck, L. Czibere, M. Panhuysen, B. Putz, J. M. Deussing, F. Holsboer, R. Landgraf, and C. W. Turck (2005) Identification of glyoxalase-I as a protein marker in a mouse model of extremes in trait anxiety. J.Neurosci. 25:4375-4384.

 

Wszolek ZK, Pfeiffer RF, Tsuboi Y, Uitti RD, McComb RD, Stoessl AJ, Audrey J. Strongosky AJ, Zimprich A, Müller-Myhsok B, Farrer MJ, Gasser T, Calne DB, Dickson DW (2004) Autosomal Dominant Parkinsonism Associated With Variable Synuclein and Tau Pathology. Neurology 11:1619-1622.

 

Zimprich A, Biskup S, Leitner P, Lichtner P, Farrer M, Lincoln S, Kachergus J, Hulihan M, Uitti RJ, Calne DB, Stoessl AJ, Pfeiffer RF, Patenge N, Carbajal IC, Vieregge P, Asmus F, Müller-Myhsok B, Dickson DW, Meitinger T, Strom TM, Wszolek ZK, Gasser T (2004) Mutations in LRRK2 Cause Autosomal-Dominant Parkinsonism with Pleomorphic Pathology. Neuron 44:601-607.

 

Zimprich A, Müller-Myhsok B, Farrer M, Leitner P, Sharma M, Hulihan M, Lockhart P, Strongosky A, Kachergus J, Calne DB, Stoessl J, Uitti RJ, Pfeiffer RF, Trenkwalder C, Homann N, Ott E, Wenzel K, Asmus F, Hardy J, Wszolek Z, Gasser T (2004) The PARK8 locus in autosomal dominant parkinsonism: confirmation of linkage and further delineation of the disease-containing interval. Am J Hum Genet 74:11-19. Erratum Am J Hum Genet. 75:534.

 

Binder EB, Salyakina D, Lichtner P, Wochnik GM, Ising M, Pütz B, Papiol S, Seaman S, Lucae S, Kohli MA, Nickel T, Künzel HE, Fuchs B, Majer M, Pfennig A, Kern N, Brunner J, Modell S, Baghai T, Deiml T, Zill P, Bondy B, Rupprecht R, Messer T, Köhnlein O, Dabitz H, Brückl T, Müller N, Pfister H, Lieb R, Mueller JC, Lõhmussaar E, Strom TM, Bettecken T, Meitinger T, Uhr M, Rein T, Holsboer F, Müller-Myhsok B (2004) Polymorphisms in FKBP5 are associated with increased recurrence of depressive episodes and rapid response to antidepressant treatment. Nat Genet. 36:1319-1325.

 

Dörr S, Lechtenböhmer N, Rau R, Herborn G, Wagner U, Müller-Myhsok B, Hansmann I, Keyszer G (2004) Association of a Specific Haplotype Across the Genes MMP1 and MMP3 with Radiographic Joint Destruction in Rheumatoid Arthritis (RA). Arthritis Res The.r 6:R199-207.

 

Giehl KA, Eckstein GN, Benet-Pages A, Tosti A, de Berker DA, Meitinger T, Müller-Myhsok B, Strom TM (2004) A gene locus responsible for the familial hair shaft abnormality pili annulati maps to chromosome 12q24.32-24.33. J Invest Dermatol. 123:1073-1077.

 

Timman C, Fuchs S, Thoma C, Lepping B, Brattig NW, Sivertsen J, Thye T, Müller-Myhsok B, Horstmann RD (2004) Promotor haploytpes of the interleukin-10 gene influence proliferation of peripheral blood cells in response to helminth antigen. Genes Immun. 5:256-260.

 

Loggen U, Boden A, Baron H, Schuster H, Tolle R, Netwich U, Dupon C, Müller-Myhsok B, Baron H, Luft FC (2003) Apolipoprotein B-100 gene mutations and cholesterol control in German patients. Atherosclerosis 166:411-412.

 

Klöting I, Poetsch M, Müller-Myhsok B, Rjasanowski I, Kerner W, Klöting N (2003) Is there relatedness between maternal lines of Type 1 diabetic patients? Diabetologia 46:441-442.

 

Agrawal S, Muller B, Bharadwaj U, Bhatnagar S, Sharma A, Khan F, Agarwal SS (2003) Microsatellite variation at 24 STR loci in three endogamous groups of Uttar Pradesh, India. Hum Biol. 75:97-104.

 

Binder EB, Holsboer F. (2003) Pharmaco-Genomics. In: Handbook of Experimental Pharmacology, Anxiety and Anxiolytic Drugs. (F Holsboer and A Ströhle, Eds.).

 

Graefe SEB, Meyer BS, Müller-Myhsok B, Rüschendorf F, Drosten T, Laue T, Steeg C, Nürnberg P, Fleischer B (2003) Murine susceptibility to Chagas' disease maps to chromsomes 5 and 17. Genes Immun. 4:321-325.

 

Thakur S, Ranjan P, Ghosbal UC, Müller-Myhsok B, Khan F, Talwar S, Agarwal S (2003) Association of human leucocyte DR and DQ antigens in Crohn's disease in Asian Indians: a family study. Trop Gastroenterol. 24:185-188.

 

Thye T, Burchard GD, Nilius M, Müller-Myhsok B, Horstmann RD (2003) Genomewide linkage analysis identifies polymorphism in the human interferon-gamma receptor affecting Helicobacter pylori infection. Am J Hum Genet. 72:448-453.

 

Hoerauf A, Kruse S, Brattig NW, Heizmann A, Müller-Myhsok B, Deichmann KA (2002) The variant Arg110Gln of human IL-13 is associated with an immunologically hyper-reactive form of onchocerciasis (sowda). Microbes Infect. 4:37 -42.

 

Giess R, Holtmann B, Braga M, Grimm T, Müller-Myhsok B, Toyka K, Sendtner K. (2002) Early Onset of Severe Familial ALS with a SOD-1 Mutation: Potential Impact of CNTF as a Candidate Modifier Gene. Am J Hum Genet. 70:1277-1286.*

 

Giess R, Holtmann B, Braga M, Grimm T, Müller-Myhsok B, Toyka K, Sendtner K (2002) Early Onset of Severe Familial ALS with a SOD-1 Mutation: Potential Impact of CNTF as a Candidate Modifier Gene. Am J Hum Genet. 70:1277-1286.

 

Gössl C. Fahrmeir L. Pütz B. Auer LM. Auer DP (2002) Fiber tracking from DTI using linear state space models: Detectability of the pyramidal tract. Neuroimage 16(2):378-388.

 

Agrawal S, Muller B, Bharadwaj U, Bhatnagar S, Khan F (2002) Distribution of allele frequencies of six STR markers in north Indians. J Forensic Sci. 47:682-685.

 

Agrawal S, Muller B, Bharadwaj U, Bhatnagar S, Khan F (2002) Evaluation of six short tandem repeat loci in forensics: north Indian populations. J Forensic Sci. 47:686-689.

 

Agrawal S, Muller B, Bharadwaj U, Bhatnagar S, Khan F (2002) Allele frequencies of microsatellite repeat loci in Bhargavas, Chaturvedis, and Brahmins of North India. J Forensic Sci. 47:678-681.

 

Binder EB, Gross RE, Nemeroff CB, Kilts CD (2002) Effects of neurotensin receptor antagonism on latent inhibition in Sprague-Dawley rats: Psychopharmacology 161: 288-295.*

 

Blessmann J, Pham Van L, Ton Nu PA, Duong Thi H, Müller-Myhsok B, Buss H, Tannich E (2002) Epidemiology of amoebiasis in a region of high incidence of amoebic liver abscess in central Vietnam. Am J Trop Med Hyg. 66:578-583

 

Winkelmann J, Müller-Myhsok B, Wittchen HU, Hock B, Prager M, Pfister H, Strohle A, Eisensehr I, Dichgans M, Gasser T, Trenkwalder C (2002) Complex segregation analysis of restless legs syndrome provides evidence for an autosomal dominant mode of inheritance in early age-at-onset families. Ann Neurol. 52: 297-302.

 

Wismüller A. Lange O. Dersch DR. Leinsinger GL. Hahn K. Pütz B. Auer D (2002) Cluster analysis of biomedical image time-series. International Journal of Computer Vision 46(2):103-128.