Publications of RG Stalla since 2000
Perez-Castro C, Renner U, Haedo MR, Stalla GK, Arzt E (2011) Cellular and molecular specificity of the pituitary gland physiology. Physiol Rev (in press)
Shan B, Gerez J, Haedo M, Fuertes M, Theodoropoulou M, Buchfelder M, Losa M, Stalla GK, Arzt E, Renner U (2011) RSUME is implicated in HIF-1-induced VEGF-A production in pituitary tumour cells. Endocr Relat Cancer (in press)
Lodeiro M, Alén BO, Mosteiro CS, Beiroa D, Nogueiras R, Theodoropoulou M, Pardo M, Gallego R, Pazos Y, Casanueva FF, Camiña JP (2011) The SHP-1 protein tyrosine phosphatase negatively modulates Akt signaling in the ghrelin/GHSR1a system. Mol Biol Cell [Epub ahead of print]
Tichomirowa MA, Barlier A, Daly AF, Jaffrain-Rea ML, Ronchi C, Yaneva M, Urban JD, Petrossians P, Elenkova A, Tabarin A, Desailloud R, Maiter D, Schürmeyer T, Cozzi R, Theodoropoulou M, Sievers C, Bernabeu I, Naves LA, Chabre O, Fajardo Montañana C, Hana V, Halaby G, Delemer B, Labarta Aizpún JI, Sonnet E, Ferrandez Longás A, Hagelstein MT, Caron P, Stalla GK, Bours V, Zacharieva S, Spada A, Brue T, Beckers A (2011) High prevalence of AIP gene mutations following focused screening in young patients with sporadic pituitary macroadenomas. Eur J Endocrinol 165(4):509-515
Sievers C, Sämann PG, Pfister H, Dimopoulou C, Czisch M, Roemmler J, Schopohl J, Stalla GK, Zihl J (2011) Cognitive function in acromegaly: description and brain volumetric correlates. Pituitary [Epub ahead of print]
Valassi E, Santos A, Yaneva M, Tóth M, Strasburger CJ, Chanson P, Wass JA, Chabre O, Pfeifer M, Feelders RA, Tsagarakis S, Trainer PJ, Franz H, Zopf K, Zacharieva S, Lamberts SW, Tabarin A, Webb SM; ERCUSYN Study Group (2011) The European Registry on Cushing's syndrome: 2-year experience. Baseline demographic and clinical characteristics. Eur J Endocrinol 165(3):383-392
Schneider HJ, Schneider M, Kreitschmann-Andermahr I, Tuschy U, Wallaschofski H, Fleck S, Faust M, Renner CI, Kopczak A, Saller B, Buchfelder M, Jordan M, Stalla GK (2011) Structured assessment of hypopituitarism after traumatic brain injury and aneurysmal subarachnoid hemorrhage in 1242 patients: the german interdisciplinary database. J Neurotrauma 28(9):1693-1698
Malysheva O, Wagner U, Wahle M, Pierer M, Wagner U, Stalla GK, Baerwald CG (2011) Hypothalamic-pituitary-adrenal axis stress test in patients with early RA: role of corticotropin-releasing hormone promoter polymorphisms. Ann Rheum Dis 70(11):2058-2059
Schneider H, Klotsche J, Wittchen H, Stalla G, Schopohl J, Kann P, Kreitschmann-Andermahr I, Wallaschofski H (2011) Effects of growth hormone replacement within the KIMS survey on estimated cardiovascular risk and predictors of risk reduction in patients with growth hormone deficiency. Clin Endocrinol (Oxf) [Epub ahead of print]
Reiter MH, Vila G, Knosp E, Baumgartner-Parzer SM, Wagner L, Stalla GK, Luger A (2011) Opposite effects of serum- and glucocorticoid-regulated kinase-1 and glucocorticoids on POMC transcription and ACTH release. Am J Physiol Endocrinol Metab 301(2):E336-E341
Occhi G, Losa M, Albiger N, Trivellin G, Regazzo D, Scanarini M, Monteserin-Garcia JL, Fröhlich B, Ferasin S, Terreni MR, Fassina A, Vitiello L, Stalla G, Mantero F, Scaroni C (2011) The glucose-dependent insulinotropic polypeptide receptor is overexpressed amongst GNAS1 mutation-negative somatotropinomas and drives growth hormone (GH)-promoter activity in GH3 cells. J Neuroendocrinol 23(7):641-649
Castillo V, Theodoropoulou M, Stalla J, Gallelli MF, Cabrera-Blatter MF, Haedo MR, Labeur M, Schmid HA, Stalla GK, Arzt E (2011) Effect of SOM230 (Pasireotide) on Corticotropic Cells: Action in Dogs with Cushing's Disease. Neuroendocrinology 94(2):124-136
Schneider HJ, Kosilek RP, Günther M, Roemmler J, Stalla GK, Sievers C, Reincke M, Schopohl J, Würtz RP (2011) A novel approach to the detection of acromegaly: accuracy of diagnosis by automatic face classification. J Clin Endocrinol Metab 96(7):2074-2080
Leistner DM, Klotsche J, Palm S, Pieper L, Stalla GK, Lehnert H, Silber S, Mäerz W, Wittchen HU, Zeiher AM (2011) Resting heart rate as a tool for risk stratification in primary care: does it provide incremental prognostic information? Eur J Cardiovasc Prev Rehabil [Epub ahead of print]
Friedrich N, Schneider H, Dörr M, Nauck M, Völzke H, Klotsche J, Sievers C, Pittrow D, Böhler S, Lehnert H, Pieper L, Wittchen HU, Wallaschofski H, Stalla GK (2011) All-cause mortality and serum insulin-like growth factor I in primary care patients. Growth Horm IGF Res 21(2):102-106
Paslakis G, Lecei O, Stalla GK, Landgraf R, Uhr M, Hamann B, Luppa P, Gilles M, Heuser I, Deuschle M (2011) The effect of treatment with ketoconazole on central CRH systems of depressed patients. Hum Psychopharmacol [Epub ahead of print]
Künzel HE, Murck H, Stalla GK, Steiger A (2011) Changes in the sleep electroencephalogram (EEG) during male to female transgender therapy. Psychoneuroendocrinology 36(7):1005-1009
Schneider HJ, Klotsche J, Silber S, Stalla GK, Wittchen HU (2011) Measuring abdominal obesity: effects of height on dirstribution of cardiometabolic risk factors using waist circumference and waist-to-height ratio. Diabetes care 34(1):e7
Kreitschmann-Andermahr I, Hartmann Y, Poll E, Schneider HJ, Buchfelder M, Stalla GK (2011) The German Database on Hypopituitarism after Traumatic Brain Injury and Aneurysmal Subarachnoid Hemorrhage - Description, Objectives and Design. Exp Clin Endocrinol Diabetes 119(1):15-20
Baur DM, Klotsche J, Hamnvik OP, Sievers C, Pieper L, Wittchen HU, Stalla GK, Schmid RM, Kales SN, Mantzoros CS (2011) Type 2 diabetes mellitus and medications for type 2 diabetes mellitus are associated with risk for and mortality from cancer in a German primary care cohort. Metabolism 80(10):1363-1371
Schneider H, Friedrich N, Klotsche J, Schipf S, Nauck M, Volzke H, Sievers C, Pieper L, März W, Wittchen HU, Stalla GK, Wallaschofski H (2011) Prediction of incident diabetes mellitus by baseline insulin-like growth factor-I levels. Eur J Endocrinol 164(2):223-229
Ebinger M, Sievers C, Klotsche J, Schneider HJ, Leonards CO, Pieper L, Wittchen HU, Stalla GK, Endres M (2010) Triglycerides and stroke risk prediction: lessons from a prospective cohort study in german primary care patients. Front Neurol 1:148
Kopczak A, von Rosen F, Krewer C, Schneider HJ, Stalla GK, Schneider M (2010) Differences in the insulin tolerance test in patients with brain damage depending on posture. Eur J Endocrinol 164(1):31-36
Labeur M, Holsboer F (2010) Molecular mechanisms of glucocorticoid receptor signalling Medicina (B Aires) 70(5):457-462
Daly AF, Tichomirowa MA, Petrossians P, Heliövaara E, Jaffrain-Rea ML, Barlier A, Naves LA, Ebeling T, Karhu A, Raappana A, Cazabat L, De Menis E, Montañana CF, Raverot G, Weil RJ, Sane T, Maiter D, Neggers S, Yaneva M, Tabarin A, Verrua E, Eloranta E, Murat A, Vierimaa O, Salmela PI, Emy P, Toledo RA, Sabaté MI, Villa C, Popelier M, Salvatori R, Jennings J, Longás AF, Labarta Aizpún JI, Georgitsi M, Paschke R, Ronchi C, Valimaki M, Saloranta C, De Herder W, Cozzi R, Guitelman M, Magri F, Lagonigro MS, Halaby G, Corman V, Hagelstein MT, Vanbellinghen JF, Barra GB, Gimenez-Roqueplo AP, Cameron FJ, Borson-Chazot F, Holdaway I, Toledo SP, Stalla GK, Spada A, Zacharieva S, Bertherat J, Brue T, Bours V, Chanson P, Aaltonen LA, Beckers A (2010) Clinical characteristics and therapeutic responses in patients with germ-line AIP mutations and pituitary adenomas: an international collaborative study. J Clin Endocrinol Metab 95(11):E373-383
Sievers C, Klotsche J, Pieper L, Schneider HJ, März W, Wittchen HU, Stalla GK, Mantzoros C (2010) Low testosterone levels predict all-cause mortality and cardiovascular events in women: a prospective cohort study in German primary care patients. Eur J Endocrinol 163(4):699-708
Petersenn S, Quabbe HJ, Schöfl C, Stalla GK, von Werder K, Buchfelder M (2010) The rational use of pituitary stimulation tests. Dtsch Arztebl Int 107(25):437-443
Theodoropoulou M, Labeur M, Paez Pereda M, Haedo M, Perone MJ, Renner U, Arzt E, Stalla GK (2010) Novel medical therapies for pituitary tumors. Front Horm Res 38:158-164
Fuertes M, Gerez J, Haedo M, Giacomini D, Páez-Pereda M, Labeur M, Stalla GK, Arzt E (2010) Cytokines and genes in pituitary tumorigenesis: RSUME role in cell biology. Front Horm Res 38:1-6
Berg C, Petersenn S, Lahner H, Herrmann BL, Buchfelder M, Droste M, Stalla GK, Strasburger CJ, Roggenbuck U, Lehmann N, Moebus S, Jöckel KH, Möhlenkamp S, Erbel R, Saller B, Mann K; Investigative Group of the Heinz Nixdorf Recall Study and the German Pegvisomant Observational Study Board and Investigators (2010) Cardiovascular risk factors in patients with uncontrolled and long-term acromegaly: comparison with matched data from the general population and the effect of disease control. J Clin Endocrinol Metab 95(8):3648-3656
Labeur M, Páez-Pereda M, Haedo M, Arzt E, Stalla GK (2010) Pituitary tumors: cell type-specific roles for BMP-4. Mol Cell Endocrinol, 326(1-2):85-88
Schaaf C, Shan B, Onofri C, Stalla GK, Arzt E, Schilling T, Perone MJ, Renner U (2010) Curcumin inhibits the growth, induces apoptosis and modulates the function of pituitary folliculostellate cells. Neuroendocrinology 91(2):200-210
Dimopoulou C, Sievers C, Wittchen HU, Pieper L, Klotsche J, Roemmler J, Schopohl J, Schneider HJ, Stalla GK (2010) Adverse anthropometric risk profile in biochemically controlled acromegalic patients: comparison with an age- and gender-matched primary care population. Pituitary 13(3):207-214
Schneider HJ, Friedrich N, Klotsche J, Pieper L, Nauck M, John U, Dörr M, Felix S, Lehnert H, Pittrow D, Silber S, Völzke H, Stalla GK, Wallaschofski H, Wittchen HU (2010) The predictive value of different measures of obesity for incident cardiovascular events and mortality. J Clin Endocrinol Metab 95(4):1777-1785
Theodoropoulou M, Stalla GK, Spengler D (2010) ZAC1 target genes and pituitary tumorigenesis. Mol Cell Endocrinol 326(1-2):60-65
Cerovac V, Monteserin-Garcia J, Rubinfeld H, Buchfelder M, Losa M, Florio T, Paez-Pereda M, Stalla GK, Theodoropoulou M (2010) The somatostatin analogue octreotide confers sensitivity to rapamycin treatment on pituitary tumor cells. Cancer Res 70(2):666-674
Sievers C, Brübach K, Saller B, Schneider HJ, Buchfelder M, Droste M, Mann K, Strasburger CJ, Stalla GK; German Pegvisomant Investigators (2010) Change of symptoms and perceived health in acromegalic patients on pegvisomant therapy: a retrospective cohort study within the German Pegvisomant Observational Study (GPOS). Clin Endocrinol (Oxf) 73(1):89-94
Kowarik M, Onofri C, Colaco T, Stalla GK, Renner U (2010) Platelet-derived growth factor (PDGF) and PDGF receptor expression and function in folliculostellate pituitary cells. Exp Clin Endocrinol Diabetes 118(2):113-120 (Epub ahead of print in 2009)
Zihl J, Schaaf L, Zillmer EA (2010) The relationship between adult neuropsychological profiles and diabetic patients' glycemic control. Appl Neuropsychol 17(1):44-51
Hennings JM, Ising M, Grautoff S, Himmerich H, Pollmächer T, Schaaf L (2010) Glucose tolerance in depressed inpatients, under treatment with mirtazapine and in healthy controls. Exp Clin Endocrinol Diabetes 118(2):98-100
Roemmler J, Steffin B, Gutt B, Schneider HJ, Sievers C, Bidlingmaier M, Schopohl J (2010) The acute effect of a single application of cabergoline on endogenou GH levels in patients with acromegaly on pegvisomant treatment. Growth Horm IGF Res 20(5):338-344
Bellodi C, Krasnykh O, Haynes N, Theodoropoulou M, Peng G, Montanaro L, Ruggero D (2010) Loss of function of the tumor suppressor DKC1 perturbs p27 translation control and contributes to pituitary tumorigenesis. Cancer Res 70(14):6026-6035
Schaaf L, Stalla GK (2009) Endocrine changes with advancing age. MMW Fortschr Med 151(42):43-45
Haedo MR, Gerez J, Fuertes M, Giacomini D, Páez-Pereda M, Labeur M, Renner U, Stalla GK, Arzt E (2009) Regulation of pituitary function by cytokines. Horm Res 72(5):266-274
Meyer S, Schaefer S, Stolk L, Arp P, Uitterlinden AG, Plöckinger U, Stalla GK, Tuschy U, Weber MM, Weise A, Pfützner A, Kann PH (2009) Association of the exon 3 deleted/full-length GHR polymorphism with recombinant growth hormone dose in growth hormone-deficient adults. Pharmacogenomics 10(10):1599-1608
Schaaf C, Shan B, Buchfelder M, Losa M, Kreutzer J, Rachinger W, Stalla G, Schilling T, Arzt E, Perone M, Renner U (2009) Curcumin acts anti-tumourigenic and hormone-suppressive in murine and human pituitary tumour cells in vitro and in vivo. Endocr Relat Cancer 16(4):1339-1350 (Epub ahead of print)
Buchfelder M, Schlaffer S, Droste M, Mann K, Saller B, Brühbach K, Stalla G, Strasburger C (2009) The German ACROSTUDY: past and present. Eur J Endocrinol 161 Suppl 1:S3-S10 (Epub ahead of print)
Theodoropoulou M, Tichomirowa MA, Sievers C, Yassouridis A, Arzberger T, Hougrand O, Deprez M, Daly AF, Petrossians P, Pagotto U, Beckers A, Stalla GK (2009) Tumor ZAC1 expression is associated with the response to somatostatin analog therapy in patients with acromegaly. Int J Cancer 125(9):2122-2126 (Epub ahead of print)
Joerges S, Schaaf L (2009) New aspects in diet for persons with type 2 diabetes. MMW Fortschr Med 151(49-50):44-6
Correa-de-Santana E, Froehlich B, Labeur M, Paez-Pereda M, Theodoropoulou M, Monteserin J, Renner U, Stalla G (2009) NOD2 receptors in adenopituitary folliculostellate cells: expression and function. J Endocrinol 203(1):111-122 (Epub ahead of print)
Jaffrain Rea ML, Angelini M, Gargano D, Tichomirowa M, Daly A, Vanbellinghen JF, D'Innocenzo E, Barlier A, Giangaspero F, Esposito V, Ventura L, Arcella A, Theodoropoulou M, Naves L, Fajardo C, Zacharieva S, Rohmer V, Brue T, Gulino A, Cantore G, Alesse E, Beckers A (2009) Expression of aryl hydrocarbon receptor (AHR) and aryl hydrocarbon receptor interacting protein (AIP) in pituitary adenomas: pathological and clinical implications. Endocr Relat Cancer 16(3):1029-1043 (Epub ahead of print)
Gorshtein A, Rubinfeld H, Kendler E, Theodoropoulou M, Cerovac V, Stalla G, Cohen Z, Hadani M, Shimon I (2009) mTOR inhibitors rapamycin and RAD001 (Everolimus) induce antiproliferative effects in GH-secreting pituitary tumor cells in vitro. Endocr Relat Cancer 16(3):1017-1027 (Epub ahead of print)
Buchfelder M, Weigel D, Droste M, Mann K, Saller B, Brübach K, Stalla GK, Bidlingmaier M, Strasburger C (2009) Pituitary tumor size in acromegaly during pegvisomant treatment: experience from MR re-evaluations of the German Pegvisomant Observational Study. Eur J Endocrinol (161(1):27-35 (Epub ahead of print)
Giacomini D, Páez-Pereda M, Stalla J, Stalla GK, Arzt E (2009) Molecular interaction of BMP-4, TGF-{beta} and estrogens in lactotrophs: impact on the PRL promoter. Mol Endocrinol 23(7):1102-1114 (Epub ahead of print)
Sievers C, Dimopoulou C, Pfister H, Lieb R, Steffin B, Roemmler J, Schopohl J, Mueller M, Schneider HJ, Ising M, Wittchen HU, Stalla GK (2009) Prevalence of mental disorders in acromegaly: a cross-sectional study in 81 acromegalic patients. Clin Endocrinol 71(5):691-701 (Epub ahead of print)
Sievers C, Sämann PG, Dose T, Dimopoulou C, Spieler D, Roemmler J, Schopohl J, Mueller M, Schneider HJ, Czisch M, Pfister H, Stalla GK (2009) Macroscopic brain architecture changes and white matter pathology in acromegaly: a clinicoradiological study. Pituitary 12(3):177-185 (Epub ahead of print in 2008)
Ebinger M, Sievers C, Ivan D, Schneider HJ, Stalla GK (2009) Is there a neuroendocrinological rationale for testosterone as a therapeutic option in depression? J Psychopharmacol 23(7):841-853 (Epub ahead of print in 2008)
Pickel J, Schneider HJ, Stalla GK (2009) Hypopituitarism and brain injury: recent advances in screening and management. F1000 Med Rep 17; 1. pii 63
Giacomini D, Haedo M, Gerez J, Druker J, Páez-Pereda M, Labeur M, Stalla GK, Arzt E (2009) Differential gene expression in models of pituitary prolactin-producing tumoral cells. Horm Res 71 Suppl 2:88-94
Arzt E, Chesnokova V, Stalla GK, Melmed S (2009) Pituitary adenoma growth: a model for cellular senescence and cytokine action. Cell Cycle 8(5):677-678
Melmed S, Colao A, Barkan A, Molitch M, Grossman AB, Kleinberg D, Clemmons D, Chanson P, Laws E, Schlechte J, Vance ML, Ho K, Giustina A; Acromegaly Consensus Group (2009) Guidelines for acromegaly management: an update. J Clin Endocrinol Metab 94(5):1509-1517
Corrêa-de-Santana E, Paez-Pereda M, Theodoropoulou M, Renner U, Stalla J, Stalla GK, Savino W (2009) Modulation of growth hormone and prolactin secretion in Trypanosoma cruzi-infected mammosomatotrophic cells. Neuroimmunomodulation 16(3):208-212
Meyer S, Schaefer S, Ivan D, Stolk L, Arp P, Uitterlinden AG, Nawroth PP, Plöckinger U, Stalla GK, Tuschy U, Weber MM, Weise A, Pfützner A, Kann PH (2009) Growth hormone dose in growth hormone-deficient adults is not associated with IGF-1 gene polymorphisms. Pharmcogenomics 10(2):293-302
Lodeiro M, Theodoropoulou M, Pardo M, Casanueva FF, Camina JP (2009) c-Src regulates Akt signaling in response to ghrelin via beta-arrestin signaling-independent and –dependent mechanisms. PLoS One 4(3):e4686
Schneider HJ, Sievers C, Klotsche J, Böhler S, Pittrow D, Lehnert H, Wittchen HU, Stalla GK (2009) Prevalence of low male testosterone levels in primary care in Germany: cross-sectional results from the DETECT study. Clin Endocrinol (Oxf) 70(3):446-454
Renner U, De Santana EC, Gerez J, Fröhlich B, Haedo M, Pereda MP, Onofri C, Stalla GK, Arzt E (2009) Intrapituitary expression and regulation of the gp130 cytokine interleukin-6 and its implication in pituitary physiology and pathophysiology. Ann N Y Acad Sci 1153:89-97
Alvarez C, Lodeiro M, Theodoropoulou M, Camina J, Casanueva F, Pazos Y (2009) Obestatin stimulates Akt signalling in gastric cancer cells through {beta}-arrestin-mediated epidermal growth factor receptor transactivation. Endocr Relat Cancer 16(2):599-611
Labeur M, Paez-Pereda M, Arzt E, Stalla GK (2009) Potential of retinoic acid derivatives for the treatment of corticotroph pituitary adenomas. Rev Endocr Metab Disord 10(2):103-109
Catania C, Sotiropoulos I, Silva R, Onofri C, Breen KC, Sousa N, Almeida OF (2009) The amyloidogenic potential and behavioral correlates of stress. Mol Psychiatry 14(1):95-105
Roemmler J, Steffin B, Gutt B, Sievers C, Bidlingmaier M, Schopohl J (2009) The effect of acute application of pegvisomant alone and in combination with octreotide on endogenous GH levels during a 6-h test in patients with acromegaly on constant pegvisomant treatment. Growth Horm IGF Res 19(3):245-252
Sievers C, Ising M, Pfister H, Dimopoulou C, Schneider H, Roemmler J, Schopohl J, Stalla G (2009) Personality in patients with pituitary adenomas is characterized by increased anxiety related traits: comparison of 70 acromegalic patients to patients with non-functioning pituitary adenomas and age- and gender matched controls. Eur J Endocrinol 160(3):367-373
Giustina A, Barkan A, Chanson P, Grossman A, Hoffman A, Ghigo E, Casanueva F, Colao A, Lamberts S, Sheppard M, Melmed S; Pituitary Society; European Neuroendocrine Association (2008) Guidelines for the treatment of growth hormone excess and growth hormone deficiency in adults. J Endocrinol Invest. 31(9):820-38
Lu A, Steiner MA, Whittle N, Vogl AM, Walser SM, Ableitner M, Refojo D, Ekker M, Rubenstein JL, Stalla GK, Singewald N, Holsboer F, Wotjak CT, Wurst W, Deussing JM (2008) Conditional CRH overexpressing mice: an animal model for stress-elicited pathologies and treatments that target the central CRH system. Mol Psychiatry. 13(11):989
Sievers C, Sämann PG, Dose T, Dimopoulou C, Spieler D, Roemmler J, Schopohl J, Mueller M, Schneider HJ, Czisch M, Pfister H, Stalla GK (2008) Macroscopic brain architecture changes and white matter pathology in acromegaly: a clinicoradiological study. Pituitary. (Epub ahead of print)
Silber S, Jarre F, Pittrow D, Klotsche J, Pieper L, Zeiher AM, Wittchen HU; DETECT-Studiengruppe. (2008) [Cardiovascular risk assessment by primary-care physicians in Germany and its lack of agreement with the Established Risk Scores (DETECT)] Med Klin (Munich) 103(9):638-45 German
Labeur M, Refojo D, Wölfel B, Stalla J, Vargas V, Theodoropoulou M, Buchfelder M, Paez-Pereda M, Arzt E, Stalla GK (2008) Interferon-gamma inhibits cellular proliferation and ACTH production in corticotroph tumor cells through a novel janus kinases-signal transducer and activator of transcription 1/nuclear factor-kappa B inhibitory signaling pathway. J Endocrinol 199(2):177-89
Tichomirowa MA, Theodoropoulou M, Daly AF, Yassouridis A, Hansen S, Lu J, Lange M, Goldbrunner RH, Stalla GK, Renner U (2008) Toll-like receptor-4 is expressed in meningiomas and mediates the antiproliferative action of paclitaxel. Int J Cancer. 123(8):1956-63
Meyer S, Haist M, Schaefer S, Ivan D, Ittner JR, Nawroth PP, Plöckinger U, Stalla GK, Tuschy U, Weber MM, Weise A, Pfützner A, Habbe N, Kann PH (2008) Association of COLIA1 Sp1 polymorphism with the effect of subcutaneously injected recombinant hGH in GH-deficient adults. Pharmacogenomics 9(8):1017-26
Kronsbein HC, Jastorff AM, Maccarrone G, Stalla G, Wurst W, Holsboer F, Turck CW, Deussing JM (2008) CRHR1-dependent effects on protein expression and posttranslational modification in AtT-20 cells. Mol Cell Endocrinol. 292(1-2):1-10
Ebinger M, Sievers C, Ivan D, Schneider HJ, Stalla GK (2008) Is there a neuroendocrinological rationale for testosterone as a therapeutic option in depression? J Psychopharmacol. (Epub ahead of print)
Florio T, Barbieri F, Spaziante R, Zona G, Hofland LJ, van Koetsveld PM, Feelders RA, Stalla GK, Theodoropoulou M, Culler MD, Dong J, Taylor JE, Moreau JP, Saveanu A, Gunz G, Dufour H, Jaquet P (2008) Efficacy of a dopamine-somatostatin chimeric molecule, BIM-23A760, in the control of cell growth from primary cultures of human non-functioning pituitary adenomas: a multi-center study. Endocr Relat Cancer 15(2):583-596
Lu A, Steiner MA, Whittle N, Vogl AM, Walser SM, Ableitner M, Refojo D, Ekker M, Rubenstein JL, Stalla GK, Singewald N, Holsboer F, Wotjak CT, Wurst W, Deussing JM (2008) Conditional mouse mutants highlight mechanisms of corticotropin-releasing hormone effects on stress-coping behavior. Mol Psychiatry 3(11):1028-42
Webb SM, Badia X, Barahona MJ, Colao A, Strasburger CJ, Tabarin A, van Aken MO, Pivonello R, Stalla G, Lamberts SW, Glusman JE (2008) Evaluation of health-related quality of life in patients with Cushing's syndrome with a new questionnaire. Eur J Endocrinol 158(5):623-30
Biller BM, Grossman AB, Stewart PM, Melmed S, Bertagna X, Bertherat J, Buchfelder M, Colao A, Hermus AR, Hofland LJ, Klibanski A, Lacroix A, Lindsay JR, Newell-Price J, Nieman LK, Petersenn S, Sonino N, Stalla GK, Swearingen B, Vance ML, Wass JA, Boscaro M (2008) Treatment of ACTH-dependent Cushing's syndrome: a consensus statement. J Clin Endocrinol Metab 93(7):2454-62
Göncz E, Strowski MZ, Grötzinger C, Nowak KW, Kaczmarek P, Sassek M, Mergler S, El-Zayat BF, Theodoropoulou M, Stalla GK, Wiedenmann B, Plöckinger U (2007) Orexin-A inhibits glucagon secretion and gene expression through a Foxo1-dependent pathway. Endocrinology 149(4):1618-26
Schneider HJ, Sievers C, Saller B, Wittchen HU, Stalla GK (2008) High prevalence of biochemical acromegaly in primary care patients with elevated insulin-like growth factor-1 levels. Clin Endocrinol (Oxf) 69(3):432-5
Schneider HJ, Klotsche J, Saller B, Böhler S, Sievers C, Pittrow D, Ruf G, März W, Erwa W, Zeiher AM, Silber S, Lehnert H, Wittchen HU, Stalla GK (2008) Associations of age-dependent IGF-I SDS with cardiovascular diseases and risk conditions: cross-sectional study in 6773 primary care patients. Eur J Endocrinol 158(2):153-61
Onofri C, Losa M, Uhl E, Stalla GK, Renner U (2008) Immunohistochemical Analysis of VEGF-C/VEGFR-3 System and Lymphatic Vessel Extent in Normal and Adenomatous Human Pituitary Tissues. Exp Clin Endocrinol Diabetes 116(3):152-7
de Kloet CS, Vermetten E, Geuze E, Lentjes EG, Heijnen CJ, Stalla GK, Westenberg HG (2008) Elevated plasma corticotrophin-releasing hormone levels in veterans with posttraumatic stress disorder. Prog Brain Res 167:287-91
Sievers C, Schneider HJ, Stalla GK (2008) Insulin-like growth factor-1 in plasma and brain: regulation in health and disease. Front Biosci 13:85-99
Schneider M, Schneider HJ, Yassouridis A, Saller B, von Rosen F, Stalla GK (2008) Predictors of anterior pituitary insufficiency after traumatic brain injury. Clin Endocrinol (Oxf) 68(2):206-12
Stalla GK (Hrsg.) (2007) Therapieleitfaden Hirnschädigung: Interdisziplinäre Aspekte bei Schädel-Hirn-Trauma und Schlaganfall, Uni-Med Bremen, ISBN 978-3-89599-382-4
Stalla GK (Hrsg.) (2007) Therapielexikon Endokrinologie und Stoffwechselkrankheiten, Springer Berlin, ISBN 978-3-540-20937-9
Meyer S, Ipek M, Keth A, Minnemann T, von Mach MA, Weise A, Ittner JR, Nawroth PP, Plöckinger U, Stalla GK, Tuschy U, Weber MM, Kann PH; German KIMS Board; German KIMS Pharmacogenetics Study Group (2007) Short stature and decreased insulin-like growth factor I (IGF-I)/growth hormone GH)-ratio in an adult GH-deficient patient pointing to additional partial GH insensitivity due to a R179C mutation of the growth hormone receptor. Growth Horm IGF Res 17(4):307-14
Giacomini D, Acuña M, Gerez J, Nagashima AC, Silberstein S, Páez-Pereda M, Labeur M, Theodoropoulou M, Renner U, Stalla GK, Arzt E (2007) Pituitary action of cytokines: focus on BMP-4 and gp130 family. Neuroendocrinology 85(2):94-100
Cota D, Steiner MA, Marsicano G, Cervino C, Herman JP, Grübler Y, Stalla J, Pasquali R, Lutz B, Stalla GK, Pagotto U (2007) Requirement of cannabinoid receptor type 1 for the basal modulation of hypothalamic-pituitary-adrenal axis function. Endocrinology 148(4):1574-81
Schneider HJ, Glaesmer H, Klotsche J, Böhler S, Lehnert H, Zeiher AM, März W, Pittrow D, Stalla GK, Wittchen HU; DETECT Study Group (2007) Accuracy of anthropometric indicators of obesity to predict cardiovascular risk. J Clin Endocrinol Metab 92(2):589-94
Böhler S, Scharnagl H, Freisinger F, Stojakovic T, Glaesmer H, Klotsche J, Pieper L, Pittrow D, Kirch W, Schneider H, Stalla GK, Lehnert H, Zeiher AM, Silber S, Koch U, Ruf G, März W, Wittchen HU; DETECT-Study Group (2007) Unmet needs in the diagnosis and treatment of dyslipidemia in the primary care setting in Germany. Atherosclerosis 190(2):397-407
Corneli G, Di Somma C, Prodam F, Bellone J, Bellone S, Gasco V, Baldelli R, Rovere S, Schneider HJ, Gargantini L, Gastaldi R, Ghizzoni L, Valle D, Salerno M, Colao A, Bona G, Ghigo E, Maghnie M, Aimaretti G (2007) Cut-off limits of the GH response to GHRH plus arginine test and IGF-I levels for the diagnosis of GH deficiency in late adolescents and young adults. Eur J Endocrinol 157(6):701-8
Schneider HJ, Corneli G, Kreitschman-Andermahr I, Rovere S, Bellone S, Bona G,Ghigo E, Aimaretti G (2007) Traumatic brain injury and hypopituitarism in children and adolescents: is the problem under-estimated? Pediatr Endocrinol Rev 4(3):205-9
Kreitschmann-Andermahr I, Schneider HJ (2007) Subarachnoid haemorrhage. Lancet 369(9565):903-4
Machens A, Schaaf L, Karges W, Frank-Raue K, Bartsch DK, Rothmund M, Schneyer U, Goretzki P, Raue F, Dralle H (2007) Age-related penetrance of endocrine tumours in multiple endocrine neoplasia type 1 (MEN1): a multicentre study of 258 gene carriers. Clin Endocrinol (Oxf) 67(4):613-22
Strasburger CJ, Buchfelder M, Droste M, Mann K, Stalla GK, Saller B, German Pegvisomant Investigators (2007) Experience from the German pegvisomant observational study. Horm Res 68 Suppl 5:70-3
Fulda S, Stalla GK, Wetter TC (2007) Prevalence of the restless legs syndrome in transsexual patients: the hormonal hypothesis revisited. J Neurol 254(12):1748-9
Carbia-Nagashima A, Gerez J, Perez-Castro C, Paez-Pereda M, Silberstein S, Stalla GK, Holsboer F, Arzt E (2007) RSUME, a small RWD-containing protein, enhances SUMO conjugation and stabilizes HIF-1alpha during hypoxia. Cell 131(2):309-23
Schneider HJ, Kreitschmann-Andermahr I, Ghigo E, Stalla GK, Agha A (2007) Hypothalamopituitary dysfunction following traumatic brain injury and aneurysmal subarachnoid hemorrhage: a systematic review. JAMA 298(12):1429-38
Schaaf L, Pickel J, Zinner K, Hering U, Höfler M, Goretzki PE, Spelsberg F, Raue F, von zur Mühlen A, Gerl H, Hensen J, Bartsch DK, Rothmund M, Schneyer U, Dralle H, Engelbach M, Karges W, Stalla GK, Höppner W (2007) Developing effective screening strategies in multiple endocrine neoplasia type 1 (MEN 1) on the basis of clinical and sequencing data of German patients with MEN 1. Exp Clin Endocrinol Diabetes 115(8):509-17
Gerez J, Bonfiglio J, Sosa S, Giacomini D, Acuña M, Nagashima AC, Perone MJ, Silberstein S, Renner U, Stalla GK, Arzt E (2007) Molecular transduction mechanisms of cytokine-hormone interactions: role of gp130 cytokines. Exp Physiol 92(5):801-6
Schneider HJ, Sämann PG, Schneider M, Croce CG, Corneli G, Sievers C, Ghigo E, Stalla GK, Aimaretti G (2007) Pituitary imaging abnormalities in patients with and without hypopituitarism after traumatic brain injury. J Endocrinol Invest 30(4):RC9-RC12
Schneider HJ, Aimaretti G, Kreitschmann-Andermahr I, Stalla GK, Ghigo E (2007) Hypopituitarism. Lancet 369(9571):1461-70
Stalla GK (Hrsg.) (2006) Therapieleitfaden Hypophysenerkrankungen, 2. Auflage, Uni-Med Bremen, ISBN 978-3-89599-885-0
Stalla GK (Hrsg.) (2006) Therapieleitfaden Transsexualität, Uni-Med Bremen, ISBN 978-3-89599-888-1
Druker J, Liberman AC, Acuña M, Giacomini D, Refojo D, Silberstein S, Pereda, MP, Stalla GK, Holsboer F, Arzt E (2006) Molecular understanding of cytokine-steroid hormone dialogue: implications for human diseases. Ann N Y Acad Sci 1088:297-306
Stalla G (2006) [Pituitary insufficiency. Underestimated complication after head and brain injuries? Interview by Johannes Weiss] Dtsch Med Wochenschr Suppl 1:46
Onofri C, Theodoropoulou M, Losa M, Uhl E, Lange M, Arzt E, Stalla GK, Renner U (2006) Localization of vascular endothelial growth factor (VEGF) receptors in normal and adenomatous pituitaries: detection of a non-endothelial function of VEGF in pituitary tumours. J Endocrinol 191(1):249-61
Schneider HJ, Rovere S, Corneli G, Croce CG, Gasco V, Rudà R, Grottoli S, Stalla GK, Soffietti R, Ghigo E, Aimaretti G (2006) Endocrine dysfunction in patients operated on for non-pituitary intracranial tumors. Eur J Endocrinol 155(4):559-66
Schneider HJ, Herrmann BL, Schneider M, Sievers C, Schaaf L, Stalla GK (2006) Discrepant results in the diagnosis of GH deficiency with the insulin-tolerance test and the GHRH plus arginine test in patients with traumatic brain injury. Eur J Endocrinol 155(4):553-7
Pittrow D, Stalla GK, Zeiher AM, Silber S, März W, Pieper L, Klotsche J, Glaesmer H, Ruf G, Schneider HJ, Lehnert H, Böhler S, Koch U, Wittchen HU (2006) [Prevalence, drug treatment and metabolic control of diabetes mellitus in primary care] Med Klin (Munich) 101(8):635-44
Labeur M, Theodoropoulou M, Sievers C, Paez-Pereda M, Castillo V, Arzt E, Stalla GK (2006) New aspects in the diagnosis and treatment of Cushing disease. Front Horm Res 35:169-78
Giacomini D, Páez-Pereda M, Theodoropoulou M, Gerez J, Nagashima AC, Chervin A, Berner S, Labeur M, Refojo D, Renner U, Stalla GK, Arzt E (2006) Bone morphogenetic protein-4 control of pituitary pathophysiology. Front Horm Res 35:22-31
Castillo V, Giacomini D, Páez-Pereda M, Stalla J, Labeur M, Theodoropoulou M, Holsboer F, Grossman AB, Stalla GK, Arzt E (2006) Retinoic acid as a novel medical therapy for Cushing's disease in dogs. Endocrinology 147(9):4438-44
Schneider HJ, Saller B, Klotsche J, März W, Erwa W, Wittchen HU, Stalla GK (2006) Opposite associations of age-dependent insulin-like growth factor-I standard deviation scores with nutritional state in normal weight and obese subjects. Eur J Endocrinol 154(5):699-706
Schneider HJ, Klotsche J, Stalla GK, Wittchen HU (2006) Obesity and risk of myocardial infarction: the INTERHEART study. Lancet 367(9516):1052; author reply 1054
Corrêa-de-Santana E, Paez-Pereda M, Theodoropoulou M, Kenji Nihei O, Gruebler Y, Bozza M, Arzt E, Villa-Verde DM, Renner U, Stalla J, Stalla GK, Savino W (2006) Hypothalamus-pituitary-adrenal axis during Trypanosoma cruzi acute infection in mice. J Neuroimmunol 173(1-2):12-22
Schneider HJ, Schneider M, Saller B, Petersenn S, Uhr M, Husemann B, von Rosen F, Stalla GK (2006) Prevalence of anterior pituitary insufficiency 3 and 12 months after traumatic brain injury. Eur J Endocrinol 154(2):259-65
Theodoropoulou M, Zhang J, Laupheimer S, Paez-Pereda M, Erneux C, Florio T, Pagotto U, Stalla GK (2006) Octreotide, a somatostatin analogue, mediates its antiproliferative action in pituitary tumor cells by altering phosphatidylinositol 3-kinase signaling and inducing Zac1 expression. Cancer Res 66(3):1576-82
Schneider HJ, Stalla GK, Buchfelder M (2006) Expert meeting: hypopituitarism after traumatic brain injury and subarachnoid haemorrhage. Acta Neurochir (Wien) 148(4):449-56
Giacomini D, Páez-Pereda M, Theodoropoulou M, Labeur M, Refojo D, Gerez J, Chervin A, Berner S, Losa M, Buchfelder M, Renner U, Stalla GK, Arzt E (2006) Bone morphogenetic protein-4 inhibits corticotroph tumor cells: involvement in the retinoic acid inhibitory action. Endocrinology 147(1):247-56
Schneider HJ, Pickel J, Stalla GK (2006) Typical female 2nd-4th finger length (2D:4D) ratios in male-to-female transsexuals-possible implications for prenatal androgen exposure. Psychoneuroendocrinology 31(2):265-9
Welt T, Engelmann M, Renner U, Erhardt A, Müller MB, Landgraf R, Holsboer F, Keck ME (2006) Temazepam triggers the release of vasopressin into the rat hypothalamic paraventricular nucleus: novel insight into benzodiazepine action on hypothalamic-pituitary-adrenocortical system activity during stress. Neuropsychopharmacology 31(12):2573-9
Hummel M, Schaaf L (2006) [Incidental increased blood glucose finding] MMW Fortschr Med 148(31-32):54-5
Himmerich H, Pollmächer T, Schaaf L (2006) [Affective disorders and diabetes] MMW Fortschr Med 148(26):37-40
Hummel M, Schaaf L, Füchtenbusch M, Standl E, Ziegler A (2006) [62 year-old patient with rapid progressive edema, low potassium and hypertension] Internist (Berl) 47(4):427, 429-33
Himmerich H, Fulda S, Schaaf L, Beitinger PA, Schuld A, Pollmächer T (2006) Changes in weight and glucose tolerance during treatment with mirtazapine. Diabetes Care 29:170-171
Sievers C, Schneider HJ, Stalla GK (2005) The genetics of hypogonadotrophic hypogonadism in the male. MMW Fortschr Med 147:32-36.
Pieper L, Wittchen HU, Glaesmer H, Klotsche J, Marz W, Stalla G, Lehnert H, Zeiher AM, Silber S, Koch U, Bohler S, Pittrow D, Ruf G (2005) Cardiovascular high-risk constellations in primary care DETECT Study 2003. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 48:1374-1382.
Vila G, Theodoropoulou M, Stalla J, Tonn JC, Losa M, Renner U, Stalla GK, Paez-Pereda M (2005) Expression and function of sonic hedgehog pathway components in pituitary adenomas: evidence for a direct role in hormone secretion and cell proliferation. J Clin Endocrinol Metab 90:6687-6694.
Ghigo E, Masel B, Aimaretti G, Leon-Carrion J, Casanueva FF, Dominguez-Morales MR, Elovic E, Perrone K, Stalla G, Thompson C, Urban R (2005) Consensus guidelines on screening for hypopituitarism following traumatic brain injury. Brain Inj. 19:711-724.
Paez-Pereda M, Giacomini D, Echenique C, Stalla GK, Holsboer F, Arzt E. (2005) Signaling processes in tumoral neuroendocrine pituitary cells as potential targets for therapeutic drugs. Curr Drug Targets Immune Endocr Metabol Disord .;5(3):259-67. Review.
Paez-Pereda M, Kuchenbauer F, Arzt E, Stalla GK. (2005) Regulation of pituitary hormones and cell proliferation by components of the extracellular matrix. Braz J Med Biol Res.;38(10):1487-94.
Schneider M, Schneider HJ, Stalla GK. (2005) Anterior Pituitary Hormone Abnormalities following Traumatic Brain Injury. J Neurotrauma .;22(9):937-46.
Gutt B, Wowra B, Alexandrov R, Uhl E, Schaaf L, Stalla GK, Schopohl J. (2005) Gamma-knife surgery is effective in normalising plasma insulin-like growth factor I in patients with acromegaly. Exp Clin Endocrinol Diabetes. ;113(4):219-24.
Wittchen HU, Glaesmer H, Marz W, Stalla G, Lehnert H, Zeiher AM, Silber S, Koch U, Bohler S, Pittrow D, Ruf G: DETECT Study Group (2005) Cardiovascular risk factors in primary care: methods and baseline prevalence rates – the DETECT program. Curr Med Res Opin 21:619-630.
Schule C, Baghai TC, Tsikolata V, Zwanzger P, Eser D, Schaaf L, Rupprecht R (2005) The combined T3/TRH test in depressed patients and healthy controls. Psychoneuroendocrinology 30:341-356.
Tichomirowa M, Theodoropoulou M, Lohrer P, Schaaf L, Losa M, Uhl E , Lange M, Arzt E, Stalla GK, Renner U (2005) Bacterial endotoxin (LPS) stimulates interleukin-6 production and inhibits growth of pituitary tumour cells expressing the Toll-like receptor 4 (Tlr4). J Neuroendocrinol. 17:152-160.
Tichomirowa M, Keck M, Paez-Pereda M, Schneider H, Renner U, Holsboer F, Stalla GK (2005) Endocrine disturbances in depression. J Endocrinol Invest. 28:89-99.
Vila G, Papazoglou M, Stalla J, Theodoropoulou M, Stalla GK, Holsboer F, Paez-Pereda M (2005) Sonic hedgehog regulates CRH signal transduction in the adult pituitary. FASEB J 19:281-283.
Newton CJ, Bilko D, Tichomirowa M, Renner U, Stalla GK (2005) The role of poly (adenosine 5´-diphosphate-ribose) polymerase in the response of pituitary tumor cells to reactive oxygen species. Endocrinology 146:1119-1127.
Schneider HJ, Oertel H, Murck H, Pollmächer T, Stalla GK, Steiger A (2005) Night sleep EEG and day time sleep propensity in adult hypopituitary patients with growth hormone deficiency before and after six months of growth hormone replacement. Psychoneuroendocrinology 30:29-37.
Labeur M, Arzt E, Stalla GK, Paez-Pereda M (2004) New perspectives in the treatment of Cushing´s syndrome. Curr Drug Targets Immune Endocr Metabol Disord. 4:335-342.
Graciarena M, Carbia-Nagashima A, Onofri C, Perez-Castro C, Giacomini D, Renner U, Stalla GK, Arzt E (2004) Involvement of the gp130 cytokine transducer in MtT/S pituitary somatotroph tumour development in an autocrine-paracrine model. Eur J Endocrinol. 151:595-604.
Theodoropoulou M, Arzberger T, Grübler Y, Jaffrain-Rea ML, Schlegel J, Schaaf L, Petrangeli E, Losa M, Stalla GK, Pagotto U (2004) Expression of epidermal growth factor receptor in neoplastic pituitary cells: evidence for a role in corticotropinoma cells. J Endocrinol. 183:385-394.
Vlotides G, Zitzmann K, Stalla GK, Auernhammer CJ (2004) Novel neurotrophin-1/B cell stimulating factor-3 (NNT-1/BSF-3)/cardiotrophin-like cytokine (CLC) – a novel gp130 cytokine with pleiotropic functions. Cytokine Growth Factor Rev. 15:325-336.
Nieschlag E, Behre HM, Bouchard P, Corrales JJ, Jones TH, Stalla GK, Webb SM, Wu FC (2004) Testosterone replacement therapy: current trends and future directions. Human Reprod Update 10:409-419.
Renner U, Paez-Pereda M, Arzt E, Stalla GK (2004) Growth factors and cytokines: function and molecular regulation in pituitary adenomas. Front Horm Res. 32:96-109.
Bohler S, Glaesmer H, Pittrow D, Lehnert H, Stalla GK, Zeiher AM, Marz W, Silber S, Wehling M, Ruf G, Reinecke A, Wittchen HU (2004) Diabetes and cardiovascular risk evaluation and management in primary care: progress and unresolved issues - rationale for a nationwide primary careproject in Germany. Exp Clin Endocrinol Diabetes. 112:57-70.
Kovalovsky D, Paez Pereda M, Labeur M, Renner U, Holsboer F, Stalla GK, Arzt E (2004) Nur77 induction and activation are necessary for interleukin-1 stimulation of proopiomelanocortin in AtT-20 corticotrophs. FEBS Letters 563:229-233.
Theodoropoulou M, Cavallari I, Barzon L, D`Agostino DM, Ferro T, Arzberger T, Grübler Y, Schaaf L, Losa M, Fallo F, Ciminale V, Stalla GK, Pagotto U (2004) Differential expression of menin in sporadic pituitary adenomas. Endocr Relat Cancer 11:333-344.
Oertel H, Schneider HJ, Stalla GK, Holsboer F, Zihl J (2004) The effect of growth hormone substitution on cognitive performance in adult patients with hypopituitarism. Psychoneuroendocrinology 29:839-850.
Schneider HJ, Stalla GK (2004) 10-minute consultation. Incidentaloma of the hypophysis. MMW Fortschr Med. 146:67-68.
Korbonits M, Slawik M, Cullen D, Ross RJ, Stalla GK, Schneider HJ, Reincke M, Bouloux P, Grossman AB (2004) A comparison of a novel testosterone bioadhesive buccal tablet, Striant, with a testosterone adhesive patch in hypogonadal males. J Clin Endocrinol Metab. 89:2039-2043.
Schneider HJ, Schneider M, von Rosen F, Uhl E, Stalla GK (2004) Ptuitary insufficiency following head injury – how common is it, and what is to be done? MMW – Fortschr Med. 146:43-44.
Scherübl H, Schaaf L, Raue F, Falss S, Zeitz M (2004) Hereditäre neuroendokrine gastroenteropankreatische Tumoren und multiple endokrine Neoplasie Typ 1: I. Aktuelle Diagnostik. Dtsch Med Wochenschr. 129:630-633
Scherübl H, Schaaf L, Raue F, Falss S, Zeitz M (2004) Hereditäre neuroendokrine gastroenteropankreatische Tumoren und multiple endokrine Neoplasie Typ 1: II. Aktuelle Therapie. Dtsch Med Wochenschr. 129:689-692
Vlotides G, Zitzmann K, Hengge S, Engelhardt D, Stalla GK, Auernhammer CJ (2004) Expression of novel neurotrophin-1/B-cell stimulating factor-3 (NNT-1/BSF-3) in murine pituitary folliculostellate TtT/GF cells: PACAP and VIP-induced stimulation of NNT-1/BSF-3 is mediated by PKA, PKC and ERK1/2 pathways. Endocrinology 145:716-727
Onofri C, Carbia Nagashima A, Schaaf L, Feirer M, Lohrer P, Stummer W, Berner S, Chervin A, Goldberg V, Stalla GK, Renner U, Arzt E (2004) Estradiol stimulates vascular endothelial growth factor and interleukin-6 in human lactotroph and lactosomatotroph pituitary adenomas. Exp Clin Endocrinol Diabetes 112:18-23
Schneider HJ, Schneider M, von Rosen F, Stalla GK (2004) Hypopituitarism following traumatic brain injury - a frequently unrecognized problem. Dtsch Aerztebl. 101:A712-717
Graciarena M., A. Carbia-Nagashima, C. Perez-Castro, D. Giacomini, M. Páez-Pereda, U. Renner, G. K. Stalla, E. Arzt (2003) Pituitary gp 130 cytokine networks. In: Pituitary and Periphery. Communication In and Out. Ed. C. J. Strasburger. BioScientifica Ltd, Bristol 197-210.
Schneider HJ, Ivan D, Stalla GK (2003) Psychische Symptomatik bei endokrinologischen Erkrankungen. NeuroTransmitter 10:60-68
Thiele J-O, Lohrer P, Schaaf L, Feirer M, Stummer W, Losa M, Lange M, Tichomirowa M, Arzt E, Stalla GK, Renner U (2003) Functional in vitro studies on the role and regulation of interleukin-6 in human somatotroph pituitary adenomas. Eur J Endocrinol. 149:455-461.
Schneider HJ, Pagotto U, Stalla GK (2003) Central effects of the somatotropic system. Eur J Endocrinol. 149:377-392.
Kuchenbauer F, Theodoropoulou M, Hopfner U, Stalla J, Renner U, Tonn JC, Low MJ, Arzt E, Stalla GK, Paez-Pereda M (2003) Laminin inhibits lactotroph proliferation and is reduced in the early prolactinoma development. Mol Cell Endocrinol. 207:13-20.
Refojo D, Liberman AC, Giacomini D, Carbia Nagashima A, Graciarena M, Echenique C, Paez Pereda M, Stalla GK, Holsboer F, Arzt E (2003) Integrating systemic information at the molecular level: cross talk between steroid receptors and cytokine signaling on different target cells. Ann N Y Acad Sci. 992:196-204.
Marsicano G, Cota D, Stalla GK, Pasquali R, Pagotto U, Lutz B (2003) Cannabinoids in energy balance and prospectives in the therapy of obesity. Curr Med Chemistry 3:81-87.
Lob S, Pickel J, Bidlingmaier M, Schaaf L, Backmund H, Gerlinghoff M, Stalla GK (2003) Serum leptin monitoring in anorectic patients during refeeding therapy. Exp Clin Endocrinol Diabetes 111:278-282.
Cavallari I, D'Agostino D, Ferro T, Rosato A, Barzon L, Pasquali C, Fogar P, Theodoropoulou M, Esposito G, Boscaro M, Pagotto U, Tebaldi E, Fallo F, Chieco-Bianchi L, and Ciminale V (2003) In situ analysis of human menin in normal and neoplastic pancreatic tissues: evidence for differential expression in exocrine and endocrine cells. J Clin Endocrinol Metab. 88:3893-3901.
Cota D, Marsicano G, Tschöp M, Grübler Y, Flachskamm C, Schubert M, Auer D, Yassourides A, Thöne-Reineke C, Ortmann S, Tomassoni F, Cervino C, Nisoli E, Linthorst ACE, Pasquali R, Lutz B, Stalla GK, Pagotto U (2003) The endogenous cannabinoid system affects energy balance via central orexigenic drive and peripheral lipogenesis. J Clin Invest. 112:423-431.
Korali Z, Wittchen HU, Pfister H, Höfler M, Oefelein W, Stalla GK (2003) Are patients with pituitary adenomas at an increased risk of mental disorders? Acta Psychiatr Scand. 107:60-68.
Deuschle M, Lecei O, Stalla GK, Landgraf R, Hamann B, Lederbogen F, Uhr M, Luppa P, Maras A, Colla M, Heuser I (2003) Steroid synthesis inhibition with ketokonazole and its effect upon the regulation of the hypothalamus-pituitary-adrenal system in healthy humans. Neuropsychopharmacology 28:379-383.
Paez Pereda M, Giacomini D, Refojo D, Nagashima AC, Hopfner U, Grübler Y, Chervin A, Goldberg V, Goya R, Hentges ST, Low MJ, Holsboer F, Stalla GK, Arzt E (2003) Involvement of bone morphogenetic protein 4 (BMP-4) in pituitary prolactinoma pathogenesis through a Smad/estrogen receptor crosstalk. Proc Natl Acad Sci USA 100:1034-1039.
Cota D, Marsicano G, Lutz B, Vicennati V, Stalla GK, Pasquali R, Pagotto U (2003) Endogenous cannabinoid system as a modulator of food intake. Int J Obes Relat Metab Disord. 27:289-301.
Castro CP, Giacomini D, Nagashima AC, Onofri C, Graciarena M, Kobayashi K, Paez-Pereda M, Renner U, Stalla GK, Arzt E (2003) Reduced expression of the cytokine transducer gp130 inhibits hormone secretion, cell growth and tumor development of pituitary lactosomatotrophic GH3 cells. Endocrinology 144:693-700.
Nagashima AC, Giacomini D, Castro CP, Pereda MP, Renner U, Stalla GK, Arzt E (2003) Transcriptional regulation of interleukin-6 in pituitary folliculo-stellate cells. Mol Cell Endocrinol. 201:47-56.
Perez Castro C., M. Páez Pereda, J. M. H. M. Reul, G. K. Stalla, F. Holsboer; E. Arzt (2002) In vivo changes of PRL levels during the T-cell dependent immune response. In: Growth and Lactogenic Hormones, ed. by L. Matera and R. Rapaport, Elsevier Science B. V., 219 – 226.
Paez Pereda M, Arzt E, Stalla GK (2002) Cushing´s syndrome: drug targets and therapeutic options. Exp Op Ther Pat. 12:1537-1546.
Renner U, Lohrer P, Schaaf L, Feirer M, Schmitt K, Onofri C, Arzt E, Stalla GK (2002) Transforming growth factor-ß stimulates vascular endothelial growth factor production by folliculostellate pituitary cells. Endocrinology 143:3759-3765.
Fiorentini C, Facchetti M, Finardi A, Sigala S, Paez Pereda M, Sher E, Spano P, Missale C (2002) Nerve growth factor and retinoic acid interactions in the control of small cell lung cancer proliferation. Eur J Endocrinol. 147:371-379.
Gambineri A, Pelusi C, Vicennati V, Pagotto U, Pasquali R (2002) Obesity and the polycystic ovary syndrome. Int J Obes Relat Metab Disord. 26:883-896.
Kovalovsky D, Refojo D, Liberman AC, Hochbaum D, Pereda MP, Coso OA, Stalla GK, Holsboer F, Arzt E (2002) Activation and induction of NUR77/NURR1 in corticotrophs by CRH/cAMP: involvement of calcium, protein kinase A, and MAPK pathways. Mol Endocrinol. 16:1638-1651.
Mohrenschlager M, Kohn FM, Bauer M, Schaaf L, Hofmann H, Ring J (2002) Late Lyme disease masking a non-functioning adenoma of the anterior lobe of the pituitary gland. Andrologia 34:162-163.
Mathias S, Schaaf LW, Sonntag A. Eosinophilia associated with olanzapine. J Clin Psychiatry 63:246-247.
Schillinger W, Schneider H, Minami K, Ferrari R, Hasenfuss G (2002) Importance of sympathetic activation for the expression of Na+-Ca2+ exchanger in end-stage failing human myocardium. Eur Heart J. 23:1118-1124.
Peteranderl C, Antonijevic IA, Steiger A, Murck H, Held K, Frieboes R-M, Uhr M, Schaaf L (2002) Nocturnal secretion of TSH and ACTH in male patients with depression and healthy controls. J Psychiatr Res. 36:189-196
Karges W. Schaaf L. Dralle H. Boehm BO. (2002) Clinical and molecular diagnosis of multiple endocrine neoplasia type 1. Langenbecks Archives of Surgery 386(8):547-552.
Lange M, Pagotto U, Renner U, Arzberger T, Oeckler R, Stalla GK (2002) The role of endothelins in the regulation of pituitary function. Experimental & Clinical Endocrinology & Diabetes 110(3):103-112.
Winkelmann J, Pagotto U, Theodoropoulou M, Tatsch,K, Saeger W, Müller A, Arzberger T, Schaaf L, Schumann EM, Trenkwalder C, Stalla GK (2002) Retention of dopamine 2 receptor mRNA and absence of the protein in craniospinal and extracranial metastasis of a malignant prolactinoma: a case report. Eur J Endocrinol. 146:81-88.
Arzt E (2001) gp130 cytokine signaling in the pituitary gland: a paradigm for cytokine-neuro-endocrine pathways. J Clin Invest 108:1729-1733.
Goebel C, Stalla GK (2001) Zyklusstörungen, Polydipsie, Visusminderung: Ist die Hypophyse schuld? MMW Fortschr Med. 143:28-30.
Perez Castro C, Carbia Nagashima A, Paez Pereda M, Goldberg V, Chervin A, Carrizo G, Molina H, Renner U, Stalla GK, Arzt E (2001) Effects of the gp130 cytokines ciliary neurotrophic factor (CNTF) and interleukin-11 on pituitary cells: CNTF receptors on human pituitary adenomas and stimulation of prolactin and GH secretion in normal rat anterior pituitary aggregate cultures. J Endocrinol. 169:539-547.
Brunner J. Stalla GK. Stalla J. Uhr M. Grabner A. Wetter TC. Bronisch T. (2001) Decreased corticotropin-releasing hormone (CRH) concentrations in the cerebrospinal fluid of eucortisolemic suicide attempters. J Psychiatr Res. 35:1-9
Gamberini A, Pelusi C, Vicennati V, Pagotto U, Pasquali R (2001) Testosterone in ageing men. Expert Opin Investig Drugs 10:477-492.
Kuchenbauer F. Hopfner U. Stalla J. Arzt E. Stalla GK. Paez-Pereda M. (2001) Extracellular matrix components regulate ACTH production and proliferation in corticotroph tumor cells. Mol Cell Endocrinol. 175:141-148.
Pagotto U. Marsicano G. Fezza F. Theodoropoulou M. Grubler Y. Stalla J. Arzberger T. Milone A. Losa M. Di Marzo V. Lutz B. Stalla GK. (2001) Normal human pituitary gland and pituitary adenomas express cannabinoid receptor type 1 and synthesize endogenous cannabinoids: First evidence for a direct role of cannabinoids on hormone modulation at the human pituitary level. J Clin Endocrinol Metab. 86:2687-2696.
Lohrer P. Gloddek J. Hopfner U. Losa M. Uhl E. Pagotto U. Stalla GK. Renner U. (2001) Vascular endothelial growth factor (VEGF) production and regulation in rodent and human pituitary tumor cells in vitro. Neuroendocrinology 74:95-105.
Paez-Pereda M. Kovalovsky D. Hopfner U. Theodoropoulou M. Pagotto U. Uhl E. Losa M. Stalla J. Grubler Y. Missale C. Arzt E. Stalla GK. (2001) Retinoic acid prevents experimental Cushing syndrome. J Clin Invest. 108:1123-1131.
Müller MB, Preil J, Renner U, Zimmermann S, Kresse AE, Stalla GK, Keck M, Holsboer F, Wurst W (2001) Expression of CRHR1 and CRHR2 in mouse pituitary and adrenal gland: implications for HPA system regulation. Endocrinology 142:4150-4153.
Pasquali R, Vicennati V, Gambineri A, Pagotto U (2001) Hormones and pathophysiology of obesity. Eat Weight Disord. 6:9-20.
Dotsch J. Dörr HG. Stalla GK. Sippell WG. (2001) Effect of glucocorticoid excess on the cortisol/cortisone ratio. Steroids 66:817-820.
Gloddek J. Lohrer P. Stalla J. Arzt E. Stalla GK. Renner U. (2001) The intrapituitary stimulatory effect of lipopolysaccharide on ACTH secretion is mediated by paracrine-acting IL-6. Exp Clin Endocrinol Diabetes 109:410-415.
Keck ME, Welt T, Wigger A, Renner U, Engelmann M, Holsboer F, Landgraf R (2001) The anxiolytic effect of the CRH1 receptor antagonist 121919 depends on innate emotionality in rats. Eur J Neurosci. 13:373-380.
Schaaf L, Theodoropoulou M, Gregori A, Leiprecht A, Trojan J, Klostermeier J, Stalla GK (2000) Thyrotropin-releasing hormone time-dependently influences thyrotropin microheterogeneity - an in vivo study in euthyroidism. J Endocrinol 166:137-143.
Karges W, Schaaf L, Dralla H, Boehm BO (2000) Concepts for screening and diagnostic follow-up in multiple endocrine neoplasia type 1 (MEN 1). Exp Clin Endocrinol Diabetes 108:334-340.
Arzt E, Kovalovsky D, Müller Igaz L, Costas M, Plazas P, Refojo D, Paez Pereda M, Reul JHMH, Stalla GK, Holsboer F (2000) Functional cross talk among cytokines, T-cell receptor and glucocorticoid receptor transcriptional activity and action. Ann. NY Acad.Sci. 917:672-677.
Lohrer P, Gloddek J, Nagashima AC, Korali Z, Paez Pereda M, Hopfner U, Arzt E, Stalla GK, Renner U (2000) Lipopolysaccharide directly stimulates the intrapituitary interleukin-6 production by folliculostellate cells via specific receptors and the p38alpha mitogen-activated protein kinase/nuclear factor-kappa B pathway. Endocrinology 141:4457-4465.
Pagotto U, Arzberger T, Theodoropoulou M, Grübler Y, Pantaloni C, Saeger W, Losa M, Journot L, Stalla GK, Spengler D (2000) The expression of the antiproliferative gene ZAC is lost or highly reduced in non-functioning adenomas. Cancer Res. 60:6794-6799.
Antonijevic IA, Stalla GK, Steiger A (2000) Modulation of the sleep electroencephalogram by estrogen replacement in postmenopausal women. Am J Obstet Gynecol 182(2):277-282.
Perez Castro C, Carbia Nagashima A, Paez Pereda M, Goldberg V, Chervin A, Largen P, Renner U, Stalla GK, Arzt E (2000) The gp130 signal-mediated cytokines IL-11 and CNTF regulate anterior pituitary function and growth through lactosomatotrophic andfolliculostellate cell receptors. Endocrinology 141:1746-1753.
Chen L, Maruyama D, Sugiyama T, Sakai T, Mogi C, Kato M, Kurotani R, Shirasawa N, Takagi T, Renner U, Kato Y, Inoue K (2000) Cytological characterization of pituitary folliculo-stellate like cell line, Tpit/F1, with special reference to ATP-mediated nNOS expression and NO secretion. Endocrinology 141:3603-3610.
Heuser I, Deuschle M, Weber B, Stalla GK, Holsboer F (2000) Increased activity of the hypothalamus-pituitary-adrenal system after treatment with the mineralcorticoid receptor antagonist spironolactone. Psychoneuroendocrinology 25(5):513-518.
Paez Pereda M, Lohrer P, Losa M, Goldberg V, Chervin A, Berner S, Molina H, Andrada J, Stalla GK, Renner U, Arzt E (2000) Interleukin-6 is inhibited by glucocorticoids and stimulates ACTH secretion and POMC expression in human pituitary adenomas. Exp Clin Endocrinol Diabetes 108:202-207.
Paez Pereda M, Missale C, Grübler Y, Arzt E, Schaaf L, Stalla GK (2000) Nerve growth factor and retinoic acid inhibit proliferation and invasion in thyroid tumor cells. Mol Cell Endocrinol. 167:99-106.
Paez Pereda M, Ledda MF, Goldberg V, Chervin A, Carrizo G, Molina A, Müller A, Renner U, Podhajcer O, Arzt E, Stalla GK (2000) High levels of matrix metalloproteinases regulate proliferation and hormone secretion in pituitary cells. J Clin Endocrinol Metab. 85:263-269.
Theodoropoulou M, Arzberger T, Grübler Y, Korali Z, Mortini P, Joba W, Heufelder AE, Stalla GK, Schaaf L (2000) Thyrotrophin receptor protein expression in normal and adenomatous human pituitary. J Endocrinol. 167:7-13.
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